Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.65 |
| ▸ | MEN1 | O00255 | 1/20 | 0.65 |
| ▸ | TP53 | P04637 | 1/20 | 0.57 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.56 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.56 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.56 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.56 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.56 |
| ▸ | PHGDH | O43175 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 3/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 3/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28096883 | 0.85 | KMT2A (0.63) | KMT2AMEN1TP53KCNMA1PDK1 | |
| SCHEMBL6535747 | 0.84 | KMT2A (0.62) | KMT2AMEN1TP53KCNMA1PDK1 | |
| SCHEMBL1733957 | 0.84 | PDK1 (0.58) | KMT2AMEN1TP53KCNMA1PDK1 | |
| SCHEMBL29740651 | 0.82 | KMT2A (0.69) | KMT2AMEN1TP53KCNMA1PDK1 | |
| SCHEMBL733777 | 0.82 | KMT2A (0.69) | KMT2AMEN1TP53KCNMA1PDK1 | |
| SCHEMBL6857920 | 0.82 | KMT2A (0.73) | KMT2AMEN1TP53KCNMA1PDK1 | |
| SCHEMBL11332310 | 0.82 | KMT2A (0.73) | KMT2AMEN1TP53KCNMA1PDK1 | |
| SCHEMBL383044 | 0.82 | PDK1 (0.59) | KMT2AMEN1TP53KCNMA1PDK1 | |
| SCHEMBL21059154 | 0.82 | KMT2A (0.67) | KMT2AMEN1TP53KCNMA1PDK1 | |
| SCHEMBL10035817 | 0.81 | KMT2A (0.77) | KMT2AMEN1TP53RAB9AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 180 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4699994-A | METHYLATING N-PHENYL CARBAMIC ACID ESTER | NIPPON KOKAN KABUSHIKI KAISHA (JP) | 1987-10-13 | — | — | US | claimed |
| CN-118355117-A | Oligonucleotide compositions and methods thereof | 波涛生命科学有限公司 | 2024-07-16 | — | — | CN | disclosed |
| CN-111936487-B | Compounds for the treatment of kinase dependent disorders | 埃克塞里艾克西斯公司 | 2024-07-09 | — | — | CN | disclosed |
| CN-111936136-B | Novel imidazopyrimidine compounds and uses thereof | 儿童医学中心公司 | 2024-07-05 | — | — | CN | disclosed |
| CN-112312909-B | Compounds for the treatment of kinase dependent disorders | 埃克塞里艾克西斯公司 | 2024-07-02 | — | — | CN | disclosed |
| CN-113710660-B | DOT1L degradation agent and application thereof | 达纳-法伯癌症研究公司 | 2024-07-02 | — | — | CN | disclosed |
| CN-118139977-A | Double-stranded oligonucleotide compositions and methods relating thereto | 波涛生命科学有限公司 | 2024-06-04 | — | — | CN | disclosed |
| CN-118139629-A | Compositions and methods for editing MECP2 transcripts | 波涛生命科学有限公司 | 2024-06-04 | — | — | CN | disclosed |
| CN-118076584-A | Esters of retinoids and bakuchiol and formulations thereof | 康纳根有限公司 | 2024-05-24 | — | — | CN | disclosed |
| CN-118055926-A | ROCK2 inhibitors and uses thereof | 哈佛大学的校长及成员们 | 2024-05-17 | — | — | CN | disclosed |
| EP-2231590-A1 | ANTITUMORAL COMPOUNDS | Pharma Mar S.A. (ES) | 2010-09-29 | — | — | EP | disclosed |
| WO-2009080761-A1 | ANTITUMORAL COMPOUNDS | PHARMA MAR, S.A. (ES) | 2009-07-02 | — | — | WO | disclosed |
| WO-2009080769-A1 | ANTITUMORAL COMPOUNDS | PHARMA MAR, S.A. (ES) | 2009-07-02 | — | — | WO | disclosed |
| EP-2032551-A1 | ANTITUMORAL DIHYDROPYRAN-2-ONE COMPOUNDS | PHARMA MAR, S.A. (ES) | 2009-03-11 | — | — | EP | disclosed |
| CN-101346468-A | Amine-containing lipids and uses thereof | MASSACHUSETTS INST TECHNOLOGY (US) | 2009-01-14 | — | — | CN | disclosed |
| WO-2007144423-A1 | ANTITUMORAL DIHYDROPYRAN-2-ONE COMPOUNDS | PHARMA MAR, S.A. (ES) | 2007-12-21 | — | — | WO | disclosed |
| CN-101010336-A | Peptide antibiotics and process for preparing same | BIOSOURCE PHARM INC (US) | 2007-08-01 | — | — | CN | disclosed |
| CN-1247535-A | Aminoepoxides from aminoaldehydes and in-situ formed halomethyl organometallic reagent | SEARLE & CO (US) | 2000-03-15 | — | — | CN | disclosed |
| US-4699994-A | METHYLATING N-PHENYL CARBAMIC ACID ESTER | NIPPON KOKAN KABUSHIKI KAISHA (JP) | 1987-10-13 | — | — | US | disclosed |
| EP-0216273-A2 | Method of manufacturing diphenylmethane dicarbamic acid esters | NIPPON KOKAN KABUSHIKI KAISHA (JP) | 1987-04-01 | — | — | EP | disclosed |