Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 1.00 |
| ▸ | MAPT | P10636 | 3/20 | 1.00 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 1.00 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 1.00 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.69 |
| ▸ | PGR | P06401 | 6/20 | 0.69 |
| ▸ | USP2 | O75604 | 5/20 | 0.69 |
| ▸ | NR3C1 | P04150 | 5/20 | 0.69 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.69 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.69 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.69 |
| ▸ | MLNR | O43193 | 1/20 | 0.69 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.69 |
| ▸ | CYP3A5 | P20815 | 1/20 | 0.69 |
| ▸ | PPARG | P37231 | 1/20 | 0.69 |
| ▸ | MEN1 | O00255 | 1/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.63 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.57 |
| ▸ | DRD2 | P14416 | 1/20 | 0.57 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Clobetasone Butyrate SCHEMBL11750078 | 1.00 | LMNA (1.00) | LMNAMAPTSMN1; SMN2NPSR1CYP3A4 | |
| Clobetasone Butyrate SCHEMBL29410388 | 1.00 | LMNA (1.00) | LMNAMAPTSMN1; SMN2NPSR1CYP3A4 | |
| Clobetasone Butyrate SCHEMBL29572705 | 1.00 | LMNA (1.00) | LMNAMAPTSMN1; SMN2NPSR1CYP3A4 | |
| Clobetasone Butyrate SCHEMBL11124627 | 1.00 | LMNA (1.00) | LMNAMAPTSMN1; SMN2NPSR1CYP3A4 | |
| Clobetasone Butyrate SCHEMBL448850 | 1.00 | LMNA (1.00) | LMNAMAPTSMN1; SMN2NPSR1CYP3A4 | |
| Clobetasone Butyrate SCHEMBL14339619 | 1.00 | LMNA (1.00) | LMNAMAPTSMN1; SMN2NPSR1CYP3A4 | |
| SCHEMBL732359 | 0.96 | LMNA (0.92) | LMNAMAPTSMN1; SMN2NPSR1CYP3A4 | |
| SCHEMBL568167 | 0.94 | LMNA (0.88) | LMNAMAPTSMN1; SMN2NPSR1CYP3A4 | |
| SCHEMBL28099304 | 0.94 | LMNA (0.88) | LMNAMAPTSMN1; SMN2NPSR1CYP3A4 | |
| SCHEMBL11748908 | 0.93 | LMNA (0.87) | LMNAMAPTSMN1; SMN2NPSR1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 5937 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4744657-A1 | THERAPEUTIC AGENT FOR HUMAN GRAFT VERSUS HOST DISEASE AND COMBINATION THEREOF | National University Corporation Okayama University (JP) | 2026-05-20 | — | — | EP | claimed |
| EP-4656202-A1 | TREATMENT OF ATOPIC DERMATITIS WITH POLYETHYLENE GLYCOL-MODIFIED INTERLEUKIN 2, GLUCOCORTICOID AND HYALURONIC ACID | Xie, Yanhui (CN) | 2025-12-03 | — | — | EP | claimed |
| EP-4598506-A1 | USE OF LONG-ACTING FLUTICASONE PROPIONATE INJECTABLE SUSPENSIONS FOR TREATING AND PREVENTING INFLAMMATIONS OF THE GASTROINTESTINAL TRACT | Eupraxia Pharmaceuticals Inc. (CA) | 2025-08-13 | — | — | EP | claimed |
| US-20250170069-A1 | NANOPREPARATION FOR JOINT ANALGESIA, AND PREPARATION METHOD AND USE THEREOF | XIANGYA HOSPITAL CENTRAL SOUTH UNIV (CN) | 2025-05-29 | — | — | US | claimed |
| CN-120000622-A | Use of a composition for delivering a drug to the skin and use of a transdermal drug delivery patch | 海伦特医药有限公司 | 2025-05-16 | — | — | CN | claimed |
| US-20250152705-A1 | COMBINATION THERAPY COMPRISING AN ANTI-IL-23 ANTIBODY AND A CORTICOSTEROID FOR TREATING PSORIASIS | SUN PHARMACEUTICAL INDUSTRIES LIMITED (IN) | 2025-05-15 | — | — | US | claimed |
| CN-119968199-A | Use of long-acting fluticasone propionate injection suspension for treating and preventing gastrointestinal tract inflammation | 优普顺药物公司 | 2025-05-09 | — | — | CN | claimed |
| EP-4495261-A1 | DETECTION OF CORTICOSTEROID EFFICIENCY BY ANALYSING THE RS37973 AND RS28362491 POLYMORPHISMS | Université de Versailles Saint-Quentin-en-Yvelines (FR) | 2025-01-22 | — | — | EP | claimed |
| US-20250000815-A1 | PATCH | MEDHERANT LTD (GB) | 2025-01-02 | — | — | US | claimed |
| EP-3431096-B1 | GLUCOCORTICOID COMBINED WITH POLYETHYLENE GLYCOL-MODIFIED INTERLEUKIN-2 FOR TREATING RESPIRATORY DISEASE | XIE YANHUI (CN) | 2024-12-18 | — | — | EP | claimed |
| EP-0844001-A1 | O/W EMULSION COMPOSITION FOR EYE DROPS | Wakamoto Pharmaceutical Co., Ltd. (JP) | 1998-05-27 | — | — | EP | claimed |
| WO-1997027862-A1 | SUPPLEMENTATION OF GLUCOCORTICOIDS | BELLARA MEDICAL PRODUCTS LIMITED (AU) | 1997-08-07 | — | — | WO | claimed |
| CN-1090173-A | A kind of prescription and preparation thereof that promotes that drug transdermal absorbs | MEDICINES SCIENCE AND TECHNOLO (CN) | 1994-08-03 | — | — | CN | claimed |
| US-5236906-A | Adrenocortical hormone and hyaluronic acid; skin diseases | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1993-08-17 | — | — | US | claimed |
| US-4844902-A | Topically applicable formulations of gyrase inhibitors in combination with corticosteroids | BAYER AKTIENGESELLSCHAFT (DE) | 1989-07-04 | — | — | US | claimed |
| EP-0241134-A1 | Pharmaceutical mixture comprising nedocromil or a salt thereof in combination with a bronchodilator | FISONS plc (GB) | 1987-10-14 | — | — | EP | claimed |
| EP-0068553-B1 | TOPICAL ANTIMICROBIAL ANTI-INFLAMMATORY COMPOSITIONS | THE PROCTER & GAMBLE COMPANY (US) | 1985-11-21 | — | — | EP | claimed |
| US-4370322-A | BETAMETHASONE, BECLOMETHASONE AND CLOBETASOL DERIVATIVES | GLAXO GROUP LIMITED (GB) | 1983-01-25 | — | — | US | claimed |
| EP-0068553-A1 | Topical antimicrobial anti-inflammatory compositions | THE PROCTER & GAMBLE COMPANY (US) | 1983-01-05 | — | — | EP | claimed |
| US-4343798-A | Topical antimicrobial anti-inflammatory compositions | THE PROCTER & GAMBLE COMPANY (US) | 1982-08-10 | — | — | US | claimed |