Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GUSB | P08236 | 7/20 | 0.53 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | TNKS | O95271 | 2/20 | 0.51 |
| ▸ | TNKS2 | Q9H2K2 | 2/20 | 0.51 |
| ▸ | PARP1 | P09874 | 1/20 | 0.51 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.43 |
| ▸ | TUBB | P07437 | 2/20 | 0.43 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.43 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.43 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.43 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.43 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.43 |
| ▸ | TUBB2A | Q13885 | 2/20 | 0.43 |
| ▸ | TUBB8 | Q3ZCM7 | 2/20 | 0.43 |
| ▸ | TUBA3E | Q6PEY2 | 2/20 | 0.43 |
| ▸ | TUBA1A | Q71U36 | 2/20 | 0.43 |
| ▸ | TUBA1C | Q9BQE3 | 2/20 | 0.43 |
| ▸ | TUBB6 | Q9BUF5 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phosphoric Acid SCHEMBL3658256 | 0.99 | GUSB (0.54) | GUSBHDAC6KDM4EHPGDTNKS | |
| SCHEMBL2370223 | 0.94 | GUSB (0.59) | GUSBHDAC6KDM4EHPGDTNKS | |
| SCHEMBL29890298 | 0.94 | GUSB (0.59) | GUSBHDAC6KDM4EHPGDTNKS | |
| Phosphoric Acid SCHEMBL3660034 | 0.93 | GUSB (0.51) | GUSBHDAC6KDM4EHPGDTNKS | |
| Phosphoric Acid SCHEMBL3660043 | 0.91 | GUSB (0.52) | GUSBHDAC6KDM4EHPGDTNKS | |
| SCHEMBL31066915 | 0.87 | GUSB (0.60) | GUSBHDAC6KDM4EHPGDTNKS | |
| SCHEMBL18258703 | 0.87 | GUSB (0.60) | GUSBHDAC6KDM4EHPGDTNKS | |
| SCHEMBL11243512 | 0.86 | GUSB (0.70) | GUSBKDM4EHPGDTNKSTNKS2 | |
| SCHEMBL4853907 | 0.84 | TNKS (0.52) | GUSBHDAC6KDM4EHPGDTNKS | |
| SCHEMBL18258694 | 0.83 | GUSB (0.76) | GUSBHDAC6KDM4EHPGDTNKS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100291591-A1 | NOVEL PLATING MEDIA | Life Technologies Corporation (US) | 2010-11-18 | — | — | US | claimed |
| EP-2209906-A2 | NOVEL PLATING MEDIA | Life Technologies Corporation (US) | 2010-07-28 | — | — | EP | claimed |
| WO-2009061733-A2 | NOVEL PLATING MEDIA | INVITROGEN CORPORATION (US) | 2009-05-14 | — | — | WO | claimed |
| US-20100291591-A1 | NOVEL PLATING MEDIA | Life Technologies Corporation (US) | 2010-11-18 | — | — | US | disclosed |
| EP-2209906-A2 | NOVEL PLATING MEDIA | Life Technologies Corporation (US) | 2010-07-28 | — | — | EP | disclosed |
| WO-2009061733-A2 | NOVEL PLATING MEDIA | INVITROGEN CORPORATION (US) | 2009-05-14 | — | — | WO | disclosed |