SCHEMBL2370223

SCHEMBL2370223

O=c1[nH]c(-c2cc(Cl)ccc2O)nc2ccc(Cl)cc12

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ GUSB P08236 7/20 0.59
▸ KDM4E B2RXH2 3/20 0.57
▸ HPGD P15428 2/20 0.57
▸ TNKS O95271 2/20 0.56
▸ TNKS2 Q9H2K2 2/20 0.56
▸ PARP1 P09874 1/20 0.56
▸ HDAC6 Q9UBN7 1/20 0.54
▸ TUBB4A P04350 2/20 0.48
▸ TUBB P07437 2/20 0.48
▸ TUBA3C P0DPH7 2/20 0.48
▸ TUBA1B P68363 2/20 0.48
▸ TUBA4A P68366 2/20 0.48
▸ TUBB4B P68371 2/20 0.48
▸ TUBB3 Q13509 2/20 0.48
▸ TUBB2A Q13885 2/20 0.48
▸ TUBB8 Q3ZCM7 2/20 0.48
▸ TUBA3E Q6PEY2 2/20 0.48
▸ TUBA1A Q71U36 2/20 0.48
▸ TUBA1C Q9BQE3 2/20 0.48
▸ TUBB6 Q9BUF5 2/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29890298 1.00 GUSB (0.59) GUSBKDM4EHPGDTNKSTNKS2
Phosphoric Acid SCHEMBL3658256 0.95 GUSB (0.54) GUSBKDM4EHPGDTNKSTNKS2
Phosphoric Acid SCHEMBL3660040 0.94 GUSB (0.53) GUSBKDM4EHPGDTNKSTNKS2
SCHEMBL18258703 0.93 GUSB (0.60) GUSBKDM4EHPGDTNKSTNKS2
SCHEMBL31066915 0.93 GUSB (0.60) GUSBKDM4EHPGDTNKSTNKS2
Phosphoric Acid SCHEMBL3660043 0.92 GUSB (0.52) GUSBKDM4EHPGDTNKSTNKS2
SCHEMBL11243512 0.92 GUSB (0.70) GUSBKDM4EHPGDTNKSTNKS2
Phosphoric Acid SCHEMBL3660034 0.91 GUSB (0.51) GUSBKDM4EHPGDTNKSTNKS2
SCHEMBL18258694 0.89 GUSB (0.76) GUSBKDM4EHPGDTNKSTNKS2
SCHEMBL31710757 0.89 GUSB (0.76) GUSBKDM4EHPGDTNKSTNKS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 98 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3526208-B1 NEW COMPOUNDS AND USES THEREOF FOR DETECTION OF TARGET MOLECULES IN A SAMPLE UNIV GENEVE (CH) 2021-03-24 — — EP claimed
US-20170012218-A1 NEAR-ULTRAVIOLET STIMULATED LIGHT-EMITTING COMPOUND AND PRODUCTION METHOD FOR SAME NANO CMS CO., LTD. (KR) 2017-01-12 — — US claimed
EP-3098284-A1 NEAR-ULTRAVIOLET STIMULATED LIGHT-EMITTING COMPOUND AND PRODUCTION METHOD FOR SAME Nano CMS Co., Ltd. (KR) 2016-11-30 — — EP claimed
US-20100291591-A1 NOVEL PLATING MEDIA Life Technologies Corporation (US) 2010-11-18 — — US claimed
EP-2209906-A2 NOVEL PLATING MEDIA Life Technologies Corporation (US) 2010-07-28 — — EP claimed
WO-2009061733-A2 NOVEL PLATING MEDIA INVITROGEN CORPORATION (US) 2009-05-14 — — WO claimed
EP-4313156-B1 DISULFIDE-BASED PRODRUG COMPOUNDS UNIV MUENCHEN LUDWIG MAXIMILIANS (DE) 2025-08-06 — — EP disclosed
US-20240207414-A1 DISULFIDE-BASED PRODRUG COMPOUND LUDWIG-MAXIMILIANS-UNIVERSITAT MUNCHEN (DE) 2024-06-27 — — US disclosed
EP-3160517-B1 WATER-SOLUBLE ACTIVATABLE MOLECULAR PROBES, INTERMEDIATES FOR THE SYNTHESIS THEREOF AND ASSOCIATED DETECTION METHODS ECOLE NORMALE SUPERIEURE LYON (FR) 2024-06-12 — — EP disclosed
US-20240156965-A1 DICHALCOGENIDE PRODRUGS LUDWIG-MAXIMILIANS-UNIVERSITAT MUNCHEN (DE) 2024-05-16 — — US disclosed
EP-4320124-A1 DICHALCOGENIDE PRODRUGS Ludwig-Maximilians-Universität München (DE) 2024-02-14 — — EP disclosed
EP-3555112-B1 FLUOROGENIC GLYCOSIDASE SUBSTRATE AND ASSOCIATED DETECTION METHOD ECOLE NORMALE SUPERIEURE LYON (FR) 2023-12-06 — — EP disclosed
US-11827620-B2 Compounds and uses thereof for detection of target molecules in a sample UNIVERSITE DE GENEVE (CH) 2023-11-28 — — US disclosed
US-20070110672-A1 SMMR (small molecule metabolite reporters) for use as in vivo glucose biosensors CERCACOR LABORATORIES, INC. 2007-05-17 — — US disclosed
US-20070110672-A1 SMMR (small molecule metabolite reporters) for use as in vivo glucose biosensors CERCACOR LABORATORIES, INC. 2007-05-17 — — US disclosed
US-5981207-A ENZYME SUBSTRATE WHICH IS DEACTIVATED BY PHOTOLYTICALLY CLEAVABLE CAGING GROUP; FOR CELL-BASED CHEMILUMINESCENT DRUG SCREENING PHARMACOPEIA, INC. (US) 1999-11-09 — — US disclosed
US-5443986-A Enzymatic analysis using substrates that yield fluorescent precipitates MOLECULAR PROBES, INC. (US) 1995-08-22 — — US disclosed
EP-0641351-A1 ENZYMATIC ANALYSIS USING SUBSTRATES THAT YIELD FLUORESCENT PRECIPITATES. MOLECULAR PROBES INC (US) 1995-03-08 — — EP disclosed
US-5316906-A Fluorescent dyes for substrates MOLECULAR PROBES, INC. (US) 1994-05-31 — — US disclosed
WO-1993004077-A1 ENZYMATIC ANALYSIS USING SUBSTRATES THAT YIELD FLUORESCENT PRECIPITATES MOLECULAR PROBES, INC. (US) 1993-03-04 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11827620-B2 Compounds and uses thereof for detection of target molecules in a sample POLRMT, SNRPE, POLI GUSB 37/4885KDM4E 4370/4885HPGD 3665/4885
US-20070110672-A1 SMMR (small molecule metabolite reporters) for use as in vivo glucose biosensors GCKR, SYMPK, SUCNR1 GUSB 281/4885KDM4E 2343/4885HPGD 1172/4885
US-20240207414-A1 DISULFIDE-BASED PRODRUG COMPOUND CBS, MSR1, P4HB GUSB 162/4885KDM4E 4718/4885HPGD 281/4885
US-20240156965-A1 DICHALCOGENIDE PRODRUGS DHCR7, DECR1, CYP27A1 GUSB 58/4885KDM4E 4690/4885HPGD 483/4885
US-20170012218-A1 NEAR-ULTRAVIOLET STIMULATED LIGHT-EMITTING COMPOUND AND PRODUCTION METHOD FOR SAME SUN2, TYR, SQLE GUSB 1639/4885KDM4E 1890/4885HPGD 168/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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