Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1A | P35348 | 3/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.54 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | BLM | P54132 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.49 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.49 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | ACHE | P22303 | 1/20 | 0.49 |
| ▸ | SCN1A | P35498 | 1/20 | 0.48 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.48 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28815671 | 0.87 | PTGS2 (0.46) | ADRA1ACYP2D6ADRA2AMEN1KMT2A | |
| SCHEMBL491187 | 0.83 | PTGS2 (0.61) | ADRA1ACYP2D6ADRA2AMEN1MAPK1 | |
| SCHEMBL31512445 | 0.83 | PTGS2 (0.61) | ADRA1ACYP2D6ADRA2AMEN1MAPK1 | |
| SCHEMBL7060376 | 0.82 | CYP2D6 (0.51) | ADRA1ACYP2D6ADRA2AMEN1MAPK1 | |
| SCHEMBL7059386 | 0.80 | TDP1 (0.47) | ADRA1ACYP2D6ADRA2AMEN1MAPK1 | |
| SCHEMBL28936060 | 0.79 | ADRA1A (0.65) | ADRA1ACYP2D6ADRA2AMEN1MAPK1 | |
| SCHEMBL23414454 | 0.79 | ADRA1A (0.59) | ADRA1ACYP2D6ADRA2AMEN1MAPK1 | |
| SCHEMBL27644642 | 0.79 | ADRA1A (0.52) | ADRA1ACYP2D6ADRA2AMEN1MAPK1 | |
| SCHEMBL7061295 | 0.79 | ADRA1A (0.47) | ADRA1ACYP2D6ADRA2AMEN1MAPK1 | |
| SCHEMBL28027161 | 0.78 | ADRA1A (0.58) | ADRA1ACYP2D6ADRA2AMEN1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8937152-B2 | Non-selective somatostatin analogues | ITALFARMACO SPA (IT) | 2015-01-20 | — | — | US | disclosed |
| EP-2225271-B1 | NEW NON-SELECTIVE SOMATOSTATIN ANALOGUES | ITALFARMACO SPA (IT) | 2013-07-31 | — | — | EP | disclosed |
| US-20100323964-A1 | NEW NON-SELECTIVE SOMATOSTATIN ANALOGUES | ITALFARMACO SPA (IT) | 2010-12-23 | — | — | US | disclosed |
| EP-2225271-A2 | NEW NON-SELECTIVE SOMATOSTATIN ANALOGUES | ITALFARMACO S.p.A. (IT) | 2010-09-08 | — | — | EP | disclosed |
| WO-2009071460-A2 | NEW NON-SELECTIVE SOMATOSTATIN ANALOGUES | ITALFARMACO SPA (IT) | 2009-06-11 | — | — | WO | disclosed |
| EP-2067786-A1 | Novel non selective analogs of somatostatin | ITALFARMACO S.p.A. (IT) | 2009-06-10 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100323964-A1 | NEW NON-SELECTIVE SOMATOSTATIN ANALOGUES | SSTR4, SSTR1, SSTR3 | ADRA1A 907/4885CYP2D6 4226/4885ADRA2A 1203/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.