Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.35 |
| ▸ | LMNA | P02545 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | F10 | P00742 | 1/20 | 0.34 |
| ▸ | GABRP | O00591 | 2/20 | 0.34 |
| ▸ | GABRD | O14764 | 2/20 | 0.34 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.34 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.34 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.34 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.34 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.34 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.34 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.34 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.34 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL358633 | 0.91 | KMT2A (0.38) | NR4A2GAAKMT2ALMNAMEN1 | |
| SCHEMBL365429 | 0.91 | TSHR (0.37) | NR4A2GAAKMT2ALMNAMEN1 | |
| SCHEMBL365515 | 0.85 | NR4A2 (0.35) | NR4A2GAAKMT2ALMNAMEN1 | |
| SCHEMBL366047 | 0.85 | KMT2A (0.48) | GAAKMT2ALMNAMEN1SMN1; SMN2 | |
| SCHEMBL365340 | 0.85 | NR4A2 (0.39) | NR4A2GAAKMT2ALMNAMEN1 | |
| SCHEMBL364860 | 0.79 | KMT2A (0.39) | NR4A2GAAKMT2ALMNAMEN1 | |
| SCHEMBL364924 | 0.78 | ALDH1A1 (0.40) | GAAKMT2ALMNAMEN1SMN1; SMN2 | |
| SCHEMBL366161 | 0.77 | ELANE (0.37) | NR4A2GAAKMT2ALMNAMEN1 | |
| SCHEMBL365428 | 0.77 | KMT2A (0.47) | GAAKMT2ALMNAMEN1SMN1; SMN2 | |
| SCHEMBL358632 | 0.77 | KMT2A (0.47) | GAAKMT2ALMNAMEN1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012007007-A1 | INHIBITORS OF HDME | EPITHERAPEUTICS APS (DK) | 2012-01-19 | — | — | WO | claimed |
| WO-2012007007-A1 | INHIBITORS OF HDME | EPITHERAPEUTICS APS (DK) | 2012-01-19 | — | — | WO | disclosed |