SCHEMBL366065

SCHEMBL366065

Cc1ccc(C2CNCCO2)cc1

nearest known ligand 0.71

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
DRD2 P14416 1/20 0.53
DRD3 P35462 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8911956 0.98 DRD2 (0.51) DRD2DRD3
SCHEMBL325236 0.91
SCHEMBL29921134 0.84 TAAR1 (0.64)
SCHEMBL1992016 0.84 TAAR1 (0.64)
SCHEMBL12609871 0.83
SCHEMBL12609873 0.83
Hydrochloric Acid SCHEMBL1995859 0.83 TAAR1 (0.63)
SCHEMBL134338 0.83 DRD2 (0.54) DRD2DRD3
SCHEMBL503067 0.83 DRD2 (0.54) DRD2DRD3
SCHEMBL503006 0.83 DRD2 (0.54) DRD2DRD3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 60 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113135835-A Method for exciting C-C bond breaking acylation and application 广州中医药大学(广州中医药研究院) 2021-07-20 CN claimed
US-4714699-A CNS AGENTS SOCIETE ANONYME DITE: LABORATOIRE L. LAFON (FR) 1987-12-22 US claimed
EP-0138716-B1 2-TOLYL-MORPHOLINE DERIVATIVES FOR THERAPEUTICAL USE LABORATOIRE L. LAFON Société anonyme dite: (FR) 1987-08-12 EP claimed
EP-0138716-A2 2-Tolyl-morpholine derivatives for therapeutical use LABORATOIRE L. LAFON Société anonyme dite: (FR) 1985-04-24 EP claimed
CN-117402124-A Aryl sulfonamide compound and anti-influenza application thereof 中国医学科学院医药生物技术研究所 2024-01-16 CN disclosed
WO-2023078392-A1 2-(ARYL-2-YL) MORPHOLINE AND DEUTERATED DERIVATIVE THEREOF, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF 上海翰森生物医药科技有限公司 2023-05-11 WO disclosed
CN-113135835-B Method for exciting C-C bond breaking acylation and application 广州中医药大学(广州中医药研究院) 2022-07-01 CN disclosed
WO-2022000031-A1 NOVEL COMPOUNDS Pakinax Pty Ltd (AU) 2022-01-06 WO disclosed
CN-113135835-A Method for exciting C-C bond breaking acylation and application 广州中医药大学(广州中医药研究院) 2021-07-20 CN disclosed
EP-3362446-B1 DOPAMINE D3 RECEPTOR ANTAGONISTS HAVING A MORPHOLINE MOIETY INDIVIOR UK LTD (GB) 2020-12-02 EP disclosed
US-10577361-B2 Dopamine D3 receptor antagonists having a morpholine moiety INDIVIOR UK LIMITED (GB) 2020-03-03 US disclosed
US-10577361-B2 Dopamine D3 receptor antagonists having a morpholine moiety INDIVIOR UK LIMITED (GB) 2020-03-03 US disclosed
US-4714699-A CNS AGENTS SOCIETE ANONYME DITE: LABORATOIRE L. LAFON (FR) 1987-12-22 US disclosed
US-4714699-A CNS AGENTS SOCIETE ANONYME DITE: LABORATOIRE L. LAFON (FR) 1987-12-22 US disclosed
US-4714699-A CNS AGENTS SOCIETE ANONYME DITE: LABORATOIRE L. LAFON (FR) 1987-12-22 US disclosed
EP-0138716-B1 2-TOLYL-MORPHOLINE DERIVATIVES FOR THERAPEUTICAL USE LABORATOIRE L. LAFON Société anonyme dite: (FR) 1987-08-12 EP disclosed
EP-0138716-B1 2-TOLYL-MORPHOLINE DERIVATIVES FOR THERAPEUTICAL USE LABORATOIRE L. LAFON Société anonyme dite: (FR) 1987-08-12 EP disclosed
EP-0138716-A2 2-Tolyl-morpholine derivatives for therapeutical use LABORATOIRE L. LAFON Société anonyme dite: (FR) 1985-04-24 EP disclosed
EP-0138716-A2 2-Tolyl-morpholine derivatives for therapeutical use LABORATOIRE L. LAFON Société anonyme dite: (FR) 1985-04-24 EP disclosed
EP-0138716-A2 2-Tolyl-morpholine derivatives for therapeutical use LABORATOIRE L. LAFON Société anonyme dite: (FR) 1985-04-24 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10577361-B2 Dopamine D3 receptor antagonists having a morpholine moiety DRD3, DRD2, SLC6A3 DRD2 2/4885DRD3 1/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.