Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 3/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.47 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.37 |
| ▸ | KDM1A | O60341 | 2/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.34 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.33 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3194570 | 0.84 | SLC6A2 (0.66) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL3194560 | 0.84 | SLC6A2 (0.66) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL3194556 | 0.84 | SLC6A2 (0.66) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL3184345 | 0.80 | SLC6A2 (0.48) | SLC6A2SLC6A4FFAR1KDM1AHDAC3 | |
| SCHEMBL3184354 | 0.80 | SLC6A2 (0.48) | SLC6A2SLC6A4FFAR1KDM1AHDAC3 | |
| SCHEMBL3184339 | 0.80 | SLC6A2 (0.48) | SLC6A2SLC6A4FFAR1KDM1AHDAC3 | |
| SCHEMBL3660838 | 0.73 | KDM1A (0.45) | SLC6A2SLC6A4FFAR1KDM1AHDAC3 | |
| SCHEMBL3660832 | 0.73 | KDM1A (0.45) | SLC6A2SLC6A4FFAR1KDM1AHDAC3 | |
| SCHEMBL3185232 | 0.72 | RAB9A (0.46) | SLC6A2SLC6A4FFAR1KDM1AHDAC3 | |
| SCHEMBL3192829 | 0.72 | RAB9A (0.46) | SLC6A2SLC6A4FFAR1KDM1AHDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2142505-A1 | SULFONAMIDES AND PHARMACEUTICAL COMPOSITIONS THEREOF | Pfizer, Inc. (US) | 2010-01-13 | — | — | EP | disclosed |
| WO-2008120093-A1 | SULFONAMIDES AND PHARMACEUTICAL COMPOSITIONS THEREOF | PFIZER INC. (US) | 2008-10-09 | — | — | WO | disclosed |