Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 4/20 | 0.44 |
| ▸ | RAB9A | P51151 | 4/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | KDM1A | O60341 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | HTR1A | P08908 | 1/20 | 0.44 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.44 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | IDO1 | P14902 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2540816 | 0.81 | L3MBTL1 (0.48) | L3MBTL1NPC1RAB9ASMN1; SMN2TAAR1 | |
| Hydrochloric Acid SCHEMBL3659014 | 0.79 | L3MBTL1 (0.52) | L3MBTL1NPC1RAB9ASMN1; SMN2TAAR1 | |
| SCHEMBL10395199 | 0.75 | SMN1; SMN2 (0.64) | L3MBTL1NPC1RAB9ASMN1; SMN2TAAR1 | |
| SCHEMBL3489021 | 0.70 | ALDH1A1 (0.49) | NPC1RAB9ASMN1; SMN2TAAR1ATM | |
| SCHEMBL1258399 | 0.70 | L3MBTL1 (0.54) | L3MBTL1NPC1RAB9ASMN1; SMN2TAAR1 | |
| Bromide SCHEMBL29261106 | 0.68 | L3MBTL1 (0.52) | L3MBTL1NPC1RAB9ASMN1; SMN2TAAR1 | |
| SCHEMBL351861 | 0.68 | IDO1 (0.43) | SMN1; SMN2ALDH1A1CYP3A4IDO1MAOA | |
| Iodide SCHEMBL29029106 | 0.68 | L3MBTL1 (0.52) | L3MBTL1NPC1RAB9ASMN1; SMN2TAAR1 | |
| Hydrochloric Acid SCHEMBL18554620 | 0.68 | L3MBTL1 (0.57) | L3MBTL1NPC1RAB9ASMN1; SMN2TAAR1 | |
| SCHEMBL1231267 | 0.68 | L3MBTL1 (0.62) | L3MBTL1NPC1RAB9ASMN1; SMN2TAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2234615-A1 | 4-IMIDAZOLIDINONES AS KV1.5 POTASSIUM CHANNEL INHIBITORS | Wyeth LLC (US) | 2010-10-06 | — | — | EP | disclosed |
| WO-2009079624-A1 | 4-IMIDAZOLIDINONES AS KV1.5 POTASSIUM CHANNEL INHIBITORS | WYETH (US) | 2009-06-25 | — | — | WO | disclosed |