Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.47 |
| ▸ | PRKCA | P17252 | 6/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | LMNA | P02545 | 2/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3654855 | 0.89 | SIRT2 (0.53) | SIRT2PRKCAALDH1A1HPGD | |
| SCHEMBL3661073 | 0.88 | SIRT2 (0.39) | SIRT2PRKCA | |
| SCHEMBL3658352 | 0.87 | SIRT2 (0.59) | SIRT2PRKCA | |
| SCHEMBL3658750 | 0.86 | SIRT2 (0.61) | SIRT2PRKCA | |
| SCHEMBL3660815 | 0.86 | SIRT2 (0.61) | SIRT2PRKCA | |
| SCHEMBL3916209 | 0.84 | SIRT2 (0.42) | SIRT2ALDH1A1LMNAHPGDTSHR | |
| SCHEMBL10754247 | 0.80 | SIRT2 (0.39) | SIRT2ALDH1A1LMNATSHR | |
| SCHEMBL3972621 | 0.78 | SIRT2 (0.49) | SIRT2PRKCAALDH1A1LMNATSHR | |
| SCHEMBL3659630 | 0.76 | SIRT2 (0.50) | SIRT2PRKCA | |
| SCHEMBL663852 | 0.74 | SIRT2 (0.53) | SIRT2PRKCA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9364424-B2 | Topical cosmetic skin lightening compositions and methods of use thereof | STIEFEL LABORATORIES, INC. (US) | 2016-06-14 | — | — | US | disclosed |
| US-20160074315-A1 | TOPICAL COSMETIC SKIN LIGHTENING COMPOSITIONS AND METHODS OF USE THEREOF | STIEFEL LABORATORIES, INC. | 2016-03-17 | — | — | US | disclosed |
| US-8574554-B2 | Uses of 4-methyl-5-hydroxy-hexanoic acid lactone | SYMRISE AG (DE) | 2013-11-05 | — | — | US | disclosed |
| EP-2219600-A1 | TOPICAL COSMETIC SKIN LIGHTENING COMPOSITIONS AND METHODS OF USE THEREOF | STIEFEL LABORATORIES, INC. (US) | 2010-08-25 | — | — | EP | disclosed |
| WO-2009067095-A1 | TOPICAL COSMETIC SKIN LIGHTENING COMPOSITIONS AND METHODS OF USE THEREOF | STIEFEL LABORATORIES, INC. (US) | 2009-05-28 | — | — | WO | disclosed |
| EP-1847588-B1 | New applications for 4-methyl-5-hydroxy hexane acid lactone | SYMRISE GMBH & CO KG (DE) | 2009-02-18 | — | — | EP | disclosed |
| EP-1602354-B1 | Use of polyglutamic acid or its salts | MEIJI SEIKA KAISHA (JP) | 2008-11-05 | — | — | EP | disclosed |
| EP-1604647-B1 | Cosmetic composition containing polyorganosiloxane-containing epsilon-polylysine polymer, and polyhydric alcohol, and production thereof | CHISSO CORP (JP) | 2008-05-07 | — | — | EP | disclosed |
| US-20070254826-A1 | Novel uses of 4-methyl-5-hydroxy-hexanoic acid lactone | SYMRISE GMBH & CO. KG (DE) | 2007-11-01 | — | — | US | disclosed |
| EP-1847588-A1 | New applications for 4-methyl-5-hydroxy hexane acid lactone | Symrise GmbH & Co. KG (DE) | 2007-10-24 | — | — | EP | disclosed |
| US-20060165636-A1 | Hair treatment composition and hair cosmetic for damaged hair | MEIJI SEIKA KAISHA, LTD. (JP) | 2006-07-27 | — | — | US | disclosed |
| US-20060018867-A1 | Cosmetic composition and production thereof | ICHIMARU PHARCOS CO., LTD | 2006-01-26 | — | — | US | disclosed |
| EP-1604647-A1 | Cosmetic composition containing polyorganosiloxane-containing epsilon-polylysine polymer, and polyhydric alcohol, and production thereof | Ichimaru Pharcos Co., Ltd. (JP) | 2005-12-14 | — | — | EP | disclosed |
| EP-1602354-A1 | HAIR TREATMENT COMPOSITION AND HAIR COSMETIC FOR DAMAGED HAIR | Meiji Seika Kaisha, Ltd. (JP) | 2005-12-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060165636-A1 | Hair treatment composition and hair cosmetic for damaged hair | CUTA, COL14A1, PRKDC | SIRT2 3118/4885PRKCA 322/4885ALDH1A1 2963/4885 |
| US-20060018867-A1 | Cosmetic composition and production thereof | CUTA, PARG, TYR | SIRT2 3392/4885PRKCA 620/4885ALDH1A1 1854/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.