Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.35 |
| ▸ | NR1D1 | P20393 | 1/20 | 0.35 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | CSF1R | P07333 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6468940 | 0.78 | TDP1 (0.49) | KMT2AMEN1ALDH1A1PKMCA2 | |
| SCHEMBL6470839 | 0.76 | MAPT (0.45) | KMT2AMEN1ALDH1A1PKMCA2 | |
| SCHEMBL4733973 | 0.74 | KMT2A (0.45) | KMT2AMEN1ALDH1A1MCOLN3ACHE | |
| SCHEMBL22581388 | 0.71 | KMT2A (0.40) | KMT2AMEN1ALDH1A1PKMCA2 | |
| SCHEMBL1725391 | 0.71 | KMT2A (0.49) | KMT2AMEN1ALDH1A1MCOLN3ACHE | |
| SCHEMBL4869129 | 0.68 | KMT2A (0.46) | KMT2AMEN1ALDH1A1MCOLN3ACHE | |
| SCHEMBL28236653 | 0.67 | KMT2A (0.46) | KMT2AMEN1ALDH1A1MCOLN3ACHE | |
| SCHEMBL25173377 | 0.67 | MEN1 (0.38) | KMT2AMEN1ALDH1A1ACHECA2 | |
| SCHEMBL1807309 | 0.66 | TDP1 (0.62) | KMT2AMEN1ALDH1A1PKMCA2 | |
| SCHEMBL7750057 | 0.66 | KMT2A (0.56) | KMT2AMEN1ALDH1A1MCOLN3ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2231159-A1 | METHOD OF TREATING ARTHRITIS | Abbott Laboratories (US) | 2010-09-29 | — | — | EP | disclosed |
| WO-2009064938-A1 | METHOD OF TREATING ARTHRITIS | ABBOTT LABORATORIES (US) | 2009-05-22 | — | — | WO | disclosed |