Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | NPY5R | Q15761 | 3/20 | 0.40 |
| ▸ | NPY1R | P25929 | 2/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.40 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25434751 | 0.87 | METAP2 (0.39) | KMT2AMEN1ALDH1A1HTTMAPT | |
| SCHEMBL29903263 | 0.86 | NSD2 (0.45) | KMT2AMEN1ALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL30802191 | 0.85 | NPY5R (0.37) | KMT2AMEN1ALDH1A1HTTMAPT | |
| SCHEMBL25176203 | 0.85 | NPY5R (0.41) | KMT2AMEN1ALDH1A1HTTNPY5R | |
| SCHEMBL30313896 | 0.85 | NPY5R (0.41) | KMT2AMEN1ALDH1A1HTTNPY5R | |
| SCHEMBL25176450 | 0.85 | KMT2A (0.38) | KMT2AMEN1ALDH1A1HTTMAPT | |
| SCHEMBL29482112 | 0.84 | NPY5R (0.38) | KMT2AMEN1ALDH1A1HTTMAPT | |
| SCHEMBL25169463 | 0.83 | KMT2A (0.50) | KMT2AMEN1ALDH1A1HTTMAPT | |
| SCHEMBL30349660 | 0.77 | KMT2A (0.46) | KMT2AMEN1ALDH1A1MAPTCA2 | |
| SCHEMBL23908116 | 0.76 | MAPT (0.42) | KMT2AMEN1ALDH1A1MAPTCA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008064116-A2 | METHOD OF PREVENTING OR TREATING ORGAN, HEMATOPOIETIC STEM CELL OR BONE MARROW TRANSPLANT REJECTION | ABBOTT LABORATORIES (US) | 2008-05-29 | — | — | WO | disclosed |