SCHEMBL366154

SCHEMBL366154

CC(N)COc1ccccc1

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.63
MAOA P21397 2/20 0.62
PTGS1 P23219 1/20 0.62
SCN4A P35499 5/20 0.61
SCN1A P35498 2/20 0.53
SCN5A Q14524 2/20 0.53
SCN9A Q15858 2/20 0.53
CYP2D6 P10635 2/20 0.53
CYP1A2 P05177 1/20 0.53
CYP3A4 P08684 1/20 0.53
CYP2C9 P11712 1/20 0.53
TSHR P16473 1/20 0.53
NFKB1 P19838 1/20 0.53
KCNK3 O14649 1/20 0.53
CACNA1F O60840 1/20 0.53
KCNK2 O95069 1/20 0.53
GBA1 P04062 1/20 0.53
HTR2A P28223 1/20 0.53
SLC6A4 P31645 1/20 0.53
HTR2B P41595 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL507119 1.00 LMNA (0.63) LMNAMAOAPTGS1SCN4ASCN1A
SCHEMBL4442204 1.00 LMNA (0.63) LMNAMAOAPTGS1SCN4ASCN1A
Hydrochloric Acid SCHEMBL21315607 0.98 LMNA (0.61) LMNAMAOAPTGS1SCN4ASCN1A
Hydrochloric Acid SCHEMBL19668691 0.98 LMNA (0.61) LMNAMAOAPTGS1SCN4ASCN1A
Hydrochloric Acid SCHEMBL28934580 0.98 LMNA (0.61) LMNAMAOAPTGS1SCN4ASCN1A
Ammonia Solution, Strong SCHEMBL9819193 0.98 LMNA (0.61) LMNAMAOAPTGS1SCN4ASCN1A
SCHEMBL17947648 0.88 MAOA (0.50) LMNAMAOAPTGS1SCN4ASCN1A
Tetradecane SCHEMBL29054435 0.87 MAOA (0.50) LMNAMAOAPTGS1SCN4ASCN1A
SCHEMBL10606913 0.85 MAOB (0.59) LMNAMAOAPTGS1CYP1A2
SCHEMBL9053577 0.84 SCN4A (0.57) LMNAMAOASCN4ASCN1ASCN5A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 169 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115745457-A High-adaptability concrete superplasticizer, preparation method and application thereof 南京博特新材料有限公司 2023-03-07 CN claimed
CN-115725035-A Slump-retaining concrete superplasticizer, preparation method and application thereof 博特新材料泰州有限公司 2023-03-03 CN claimed
EP-2763990-B1 PYRROLOPYRAZINE KINASE INHIBITORS HOFFMANN LA ROCHE (CH) 2017-02-22 EP claimed
US-8658646-B2 Pyrrolopyrazine kinase inhibitors HOFFMANN-LAROCHE INC. (US) 2014-02-25 US claimed
EP-0619294-B1 PROCESS FOR PRODUCING 1-PHENOXY-2-AMINOPROPANE IDEMITSU KOSAN CO (JP) 1997-12-29 EP claimed
US-5420352-A Reaction of alcohol with ammonia to form amine in a solvent in the presence of copper chromium catalyst and hydrogen IDEMITSU KOSAN CO., LTD. (JP) 1995-05-30 US claimed
EP-0619294-A1 PROCESS FOR PRODUCING 1-PHENOXY-2-AMINOPROPANE IDEMITSU KOSAN COMPANY LIMITED (JP) 1994-10-12 EP claimed
EP-0147510-B1 DIBENZOPYRAN DERIVATIVES FISONS CORPORATION (US) 1989-08-16 EP claimed
US-4569994-A Dibenzo[b,d]pyranyloxyaminopropanols PENNWALT CORPORATION 1986-02-11 US claimed
EP-0147510-A1 Dibenzopyran derivatives FISONS CORPORATION (US) 1985-07-10 EP claimed
CN-117843968-A Multifunctional solid concrete superplasticizer, preparation method and application 江苏苏博特新材料股份有限公司 2024-04-09 CN disclosed
WO-2023227795-A1 BIOCATALYSTS FOR ORGANIC SYNTHESIS ENGINZYME AB (SE) 2023-11-30 WO disclosed
CN-116987006-A Novel method for preparing p-aminophenylacetonitrile by reducing sodium sulfide 安徽科芯微流化工科技有限公司 2023-11-03 CN disclosed
CN-110951720-B Immobilized proteins and uses thereof 恩制因塞米公司 2023-08-18 CN disclosed
EP-3910337-B1 METHOD FOR CATALYZING AN ENZYME-CATALYZED REACTION ENGINZYME AB (SE) 2023-08-09 EP disclosed
EP-0010256-A2 Process for preparing symmetric 1,3-disubstituted ureas BASF Aktiengesellschaft (DE) 1980-04-30 EP disclosed
EP-0006614-A2 Pyridyl- and imidazopyridyloxypropanolamines, process for preparing the same and pharmaceutical compositions containing the same MERCK & CO. INC. (US) 1980-01-09 EP disclosed
EP-0004920-A1 Derivatives of carbazolyl-4-oxypropanolamine, methods for their preparation and medicines containing them Roche Diagnostics GmbH (DE) 1979-10-31 EP disclosed
US-4147869-A ADRENERGIC BLOCKING AGENTS FOR TREATMENT OF ANGINA PECTORIS, ARRHYTHMIA AND HYPERTENSION OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1979-04-03 US disclosed
US-RE29324-E N-Substituted aspartyl peptide amides G. D. SEARLE & CO. (US) 1977-07-26 US disclosed