Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 15/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12812542 | 0.88 | AR (0.53) | AR | |
| SCHEMBL632871 | 0.84 | AR (0.69) | AR | |
| SCHEMBL13185084 | 0.83 | AR (0.52) | AR | |
| SCHEMBL3527308 | 0.82 | AR (0.62) | AR | |
| SCHEMBL3661785 | 0.82 | AR (0.69) | AR | |
| SCHEMBL1772934 | 0.81 | AR (0.79) | AR | |
| SCHEMBL1978289 | 0.80 | AR (0.48) | AR | |
| SCHEMBL30939578 | 0.80 | AR (0.48) | AR | |
| SCHEMBL629858 | 0.80 | AR (1.00) | AR | |
| SCHEMBL1972838 | 0.80 | AR (0.63) | AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9682960-B2 | Non-steroidal antiandrogens and selective androgen receptor modulators with a pyridyl moiety | ENDORECHERCHE, INC. (CA) | 2017-06-20 | — | — | US | disclosed |
| US-9682960-B2 | Non-steroidal antiandrogens and selective androgen receptor modulators with a pyridyl moiety | ENDORECHERCHE, INC. (CA) | 2017-06-20 | — | — | US | disclosed |
| WO-2015089634-A9 | NON-STEROIDAL ANTIANDROGENS AND SELECTIVE ANDROGEN RECEPTOR MODULATORS WITH A PYRIDYL MOIETY | ENDORECHERCHE, INC. (CA) | 2016-01-14 | — | — | WO | disclosed |
| WO-2015089634-A1 | NON-STEROIDAL ANTIANDROGENS AND SELECTIVE ANDROGEN RECEPTOR MODULATORS WITH A PYRIDYL MOIETY | ENDORECHERCHE, INC. (CA) | 2015-06-25 | — | — | WO | disclosed |
| US-20150175576-A1 | NON-STEROIDAL ANTIANDROGENS AND SELECTIVE ANDROGEN RECEPTOR MODULATORS WITH A PYRIDYL MOIETY | ENDORECHERCHE, INC. (CA) | 2015-06-25 | — | — | US | disclosed |
| US-20150175576-A1 | NON-STEROIDAL ANTIANDROGENS AND SELECTIVE ANDROGEN RECEPTOR MODULATORS WITH A PYRIDYL MOIETY | ENDORECHERCHE, INC. (CA) | 2015-06-25 | — | — | US | disclosed |
| EP-2419422-B1 | IMIDAZOLIDINE-2,4-DIONE DERIVATIVES AND USE THEREOF AS A MEDICAMENT | IPSEN PHARMA SAS (FR) | 2014-10-15 | — | — | EP | disclosed |
| US-8624037-B2 | Imidazolidine-2,4-dione derivatives and use thereof as a medicament | IPSEN PHARMA S.A.S. (FR) | 2014-01-07 | — | — | US | disclosed |
| US-20120095068-A1 | IMIDAZOLIDINE-2,4-DIONE DERIVATIVES AND USE THEREOF AS A MEDICAMENT | IPSEN PHARMA S.A.S. (FR) | 2012-04-19 | — | — | US | disclosed |
| EP-2419422-A1 | IMIDAZOLIDINE-2,4-DIONE DERIVATIVES AND USE THEREOF AS A MEDICAMENT | IPSEN PHARMA S.A.S. (FR) | 2012-02-22 | — | — | EP | disclosed |
| WO-2010119194-A1 | IMIDAZOLIDINE-2,4-DIONE DERIVATIVES AND USE THEREOF AS A MEDICAMENT | IPSEN PHARMA S.A.S. (FR) | 2010-10-21 | — | — | WO | disclosed |
| US-7803826-B2 | Imidazolidine derivatives | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2010-09-28 | — | — | US | disclosed |
| US-20070249697-A1 | Novel Imidazolidine Derivatives | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2007-10-25 | — | — | US | disclosed |
| EP-1775289-A1 | NOVEL IMIDAZOLIDINE DERIVATIVES | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2007-04-18 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120095068-A1 | IMIDAZOLIDINE-2,4-DIONE DERIVATIVES AND USE THEREOF AS A MEDICAMENT | MKI67, CCNI, CCNA1 | AR 2479/4885 |
| US-20150175576-A1 | NON-STEROIDAL ANTIANDROGENS AND SELECTIVE ANDROGEN RECEPTOR MODULATORS WITH A PYRIDYL MOIETY | AR, SHBG, SRD5A1 | AR 1/4885 |
| US-20070249697-A1 | Novel Imidazolidine Derivatives | CYP3A4, CYP4B1, OPRD1 | AR 3146/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.