SCHEMBL3661809

SCHEMBL3661809

O=C(O)c1c2c(c3ccccc3c1C(=O)O)CCC2

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CDC7 O00311 1/20 0.44
EEF2K O00418 1/20 0.44
PLK4 O00444 1/20 0.44
DYRK3 O43781 1/20 0.44
PRKD3 O94806 1/20 0.44
MAP4K4 O95819 1/20 0.44
PRKCG P05129 1/20 0.44
AXL P30530 1/20 0.44
AKT1 P31749 1/20 0.44
AKT2 P31751 1/20 0.44
SYK P43405 1/20 0.44
MAPKAPK2 P49137 1/20 0.44
CLK2 P49760 1/20 0.44
GSK3B P49841 1/20 0.44
RPS6KA3 P51812 1/20 0.44
PLK1 P53350 1/20 0.44
CSNK2A1 P68400 1/20 0.44
CSNK1G2 P78368 1/20 0.44
BTK Q06187 1/20 0.44
TYRO3 Q06418 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL480352 0.96 CDC7 (0.48) CDC7EEF2KPLK4DYRK3PRKD3
SCHEMBL3458298 0.94 CDC7 (0.47) CDC7EEF2KPLK4DYRK3PRKD3
SCHEMBL84141 0.92 CDC7 (0.46) CDC7EEF2KPLK4DYRK3PRKD3
SCHEMBL6682958 0.81 KDM4E (0.50) CDC7EEF2KPLK4DYRK3PRKD3
SCHEMBL15845324 0.81 KDM4E (0.51) CDC7EEF2KPLK4DYRK3PRKD3
SCHEMBL5432747 0.81 FOLH1 (0.44) CDC7EEF2KPLK4DYRK3PRKD3
SCHEMBL7604525 0.77 WDR5 (0.50) CDC7EEF2KPLK4DYRK3PRKD3
SCHEMBL54422 0.76 KDM4E (0.58) ALDH1A1KDM4EHPGDKMT2AMEN1
SCHEMBL7603901 0.76 KDM4E (0.47) CDC7EEF2KPLK4DYRK3PRKD3
SCHEMBL11217935 0.74 KDM4E (0.48) CDC7EEF2KPLK4DYRK3PRKD3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20160168321-A1 HEAT RESISTANT POLYETHYLENE TEREPHTHALATE AND A PROCESS FOR THE PREPARATION OF THE SAME ESTER INDUSTRIES LIMITED (IN) 2016-06-16 US claimed
EP-2999733-A1 HEAT RESISTANT POLYETHYLENE TEREPHTHALATE AND A PROCESS FOR THE PREPARATION OF THE SAME Ester Industries Limited (IN) 2016-03-30 EP claimed
US-20070232763-A1 Naphthalate based polyester resin compositions FUTURA POLYESTERS LIMITED (IN) 2007-10-04 US claimed
US-20030129399-A1 Wrapped cord DURAFIBER TECHNOLOGIES (DFT) OPERATIONS, LLC. (FORMERLY KNOWN AS PERFORMANCE FIBERS OPERATIONS, INC.) 2003-07-10 US claimed
US-6539698-B2 Wrapped cord CONTINENTAL AG (DE) 2003-04-01 US claimed
US-20020139465-A1 Wrapped cord CONTINENTAL REIFEN DEUTSCHLAND GMBH (DE) 2002-10-03 US claimed
US-20020095928-A1 Wrapped cord CONTINENTAL AG (DE) 2002-07-25 US claimed
EP-3177663-B1 A PROCESS FOR PREPARATION OF MODIFIED POLYETHYLENE TERPHTHALATE WITH IMPROVED BARRIER, MECHANICAL AND THERMAL PROPERTIES AND PRODUCTS THEREOF ESTER INDUSTRIES LTD (IN) 2021-04-14 EP disclosed
EP-3107949-B1 SULFONATED CO-POLYESTERS AND METHOD FOR MANUFACTURING ESTER INDUSTRIES LTD (IN) 2020-07-15 EP disclosed
EP-3177664-B1 MODIFIED POLYBUTYLENE NAPHTHALATE FOR IMPROVED PERFORMANCE AND PROCESS OF MAKING THEREOF ESTER INDUSTRIES LTD (IN) 2019-04-10 EP disclosed
US-10174162-B2 Process for preparation of modified polyethylene terphthalate with improved barrier, mechanical and thermal properties and products thereof ESTER INDUSTRIES LIMITED (IN) 2019-01-08 US disclosed
US-10167363-B2 Modified polybutylene naphthalate for improved performance and process of making thereof ESTER INDUSTRIES LIMITED (IN) 2019-01-01 US disclosed
US-9790321-B2 Heat resistant polyethylene terephthalate and a process for the preparation of the same ESTER INDUSTRIES LIMITED (IN) 2017-10-17 US disclosed
US-6855423-B2 Wrapped cord CONTINENTAL AG (DE) 2005-02-15 US disclosed
US-20030129399-A1 Wrapped cord DURAFIBER TECHNOLOGIES (DFT) OPERATIONS, LLC. (FORMERLY KNOWN AS PERFORMANCE FIBERS OPERATIONS, INC.) 2003-07-10 US disclosed
US-6539698-B2 Wrapped cord CONTINENTAL AG (DE) 2003-04-01 US disclosed
US-20020139465-A1 Wrapped cord CONTINENTAL REIFEN DEUTSCHLAND GMBH (DE) 2002-10-03 US disclosed
US-20020095928-A1 Wrapped cord CONTINENTAL AG (DE) 2002-07-25 US disclosed
EP-1225261-A1 Wrapped cord Continental AG (DE) 2002-07-24 EP disclosed
EP-1225260-A1 Wrapped cord Continental AG (DE) 2002-07-24 EP disclosed