Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | NR4A2 | P43354 | 4/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | F2 | P00734 | 1/20 | 0.36 |
| ▸ | PLAU | P00749 | 1/20 | 0.36 |
| ▸ | ELANE | P08246 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | EGFR | P00533 | 1/20 | 0.34 |
| ▸ | SRC | P12931 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL365899 | 0.89 | LMNA (0.40) | KMT2AMEN1NR4A2GAALMNA | |
| SCHEMBL366188 | 0.87 | NR4A2 (0.39) | KMT2AMEN1NR4A2GAALMNA | |
| SCHEMBL364533 | 0.83 | NR4A2 (0.45) | KMT2AMEN1NR4A2GAALMNA | |
| SCHEMBL366180 | 0.83 | MAPT (0.43) | KMT2AMEN1GAALMNASMN1; SMN2 | |
| SCHEMBL364929 | 0.75 | NR4A2 (0.41) | KMT2AMEN1NR4A2GAALMNA | |
| SCHEMBL367527 | 0.74 | NR4A2 (0.41) | KMT2AMEN1NR4A2GAALMNA | |
| SCHEMBL364931 | 0.74 | NR4A2 (0.50) | KMT2AMEN1NR4A2GAALMNA | |
| SCHEMBL364927 | 0.74 | SRC (0.51) | KMT2AMEN1NR4A2GAALMNA | |
| SCHEMBL365565 | 0.73 | KMT2A (0.52) | KMT2AMEN1NR4A2GAALMNA | |
| SCHEMBL365826 | 0.72 | KMT2A (0.48) | KMT2AMEN1NR4A2GAALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012007007-A1 | INHIBITORS OF HDME | EPITHERAPEUTICS APS (DK) | 2012-01-19 | — | — | WO | claimed |
| WO-2012007007-A1 | INHIBITORS OF HDME | EPITHERAPEUTICS APS (DK) | 2012-01-19 | — | — | WO | disclosed |