Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | NR4A2 | P43354 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.45 |
| ▸ | ATM | Q13315 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | IDO1 | P14902 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | ELANE | P08246 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL365014 | 0.87 | KDM4E (0.48) | KMT2ANR4A2MEN1L3MBTL1SMN1; SMN2 | |
| SCHEMBL364969 | 0.87 | KDM4E (0.53) | KMT2AMEN1ATMMAPTIDO1 | |
| SCHEMBL364594 | 0.86 | EGFR (0.44) | KMT2ANR4A2MEN1L3MBTL1SMN1; SMN2 | |
| SCHEMBL364927 | 0.84 | SRC (0.51) | KMT2ANR4A2MEN1SMN1; SMN2MAPT | |
| SCHEMBL364931 | 0.84 | NR4A2 (0.50) | KMT2ANR4A2MEN1SMN1; SMN2MAPT | |
| SCHEMBL365408 | 0.83 | ALDH1A1 (0.46) | KMT2ANR4A2MEN1L3MBTL1SMN1; SMN2 | |
| SCHEMBL364207 | 0.83 | EGFR (0.47) | KMT2ANR4A2MEN1L3MBTL1SMN1; SMN2 | |
| SCHEMBL364294 | 0.82 | KMT2A (0.44) | KMT2ANR4A2MEN1L3MBTL1SMN1; SMN2 | |
| SCHEMBL364973 | 0.82 | KMT2A (0.42) | KMT2ANR4A2MEN1L3MBTL1SMN1; SMN2 | |
| SCHEMBL364281 | 0.82 | NR4A2 (0.48) | KMT2ANR4A2MEN1SMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012007007-A1 | INHIBITORS OF HDME | EPITHERAPEUTICS APS (DK) | 2012-01-19 | — | — | WO | claimed |
| WO-2012007007-A1 | INHIBITORS OF HDME | EPITHERAPEUTICS APS (DK) | 2012-01-19 | — | — | WO | disclosed |
| WO-2012007008-A1 | INHIBITORS OF HDME | EPITHERAPEUTICS APS (DK) | 2012-01-19 | — | — | WO | disclosed |