Pyridine

Pyridine

SCHEMBL366216

BrCCBr.c1ccncc1

nearest known ligand 0.64

Full drug profile on Sugi Atlas →

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 3/20 0.64
TSHR P16473 2/20 0.64
NAPRT Q6XQN6 1/20 0.64
HSD17B10 Q99714 1/20 0.36
NOTUM Q6P988 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Pyridine SCHEMBL2469903 0.84 TSHR (0.90) TDP1TSHRNAPRTNOTUM
Pyridine SCHEMBL29006289 0.84 TSHR (0.53) TDP1TSHRNAPRT
Pyridine SCHEMBL8984834 0.83
Pyridine SCHEMBL567569 0.83
Pyridine SCHEMBL6691934 0.83
Pyridine SCHEMBL367210 0.83
Pyridine SCHEMBL6466367 0.81
Pyridine SCHEMBL16 0.80
Pyridine SCHEMBL933604 0.80 TSHR (1.00) TDP1TSHRNAPRTNOTUM
Pyridine SCHEMBL1654468 0.80

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 69 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120136189-A1 BUFFERED IONIC LIQUIDS FOR OLEFIN DIMERIZATION CONOCOPHILLIPS COMPANY - IP SERVICES GROUP (US) 2012-05-31 US claimed
WO-2011112514-A1 BUFFERED IONIC LIQUIDS FOR OLEFIN DIMERIZATION CONOCOPHILLIPS COMPANY (US) 2011-09-15 WO claimed
US-20110185788-A1 IONIC LIQUIDS AS SOLVENTS IN HEADSPACE GAS CHROMATOGRAPHY KOCH PETER 2011-08-04 US claimed
EP-2275090-A2 Microparticles prepared using an ionic liquid Novartis AG (CH) 2011-01-19 EP claimed
US-20100239524-A1 MICROPARTICLES PREPARED USING AN IONIC LIQUID NOVARTIS AG (CH) 2010-09-23 US claimed
US-7569149-B2 Ionic liquids as solvents in headspace gas chromatography NOVARTIS AG (CH) 2009-08-04 US claimed
US-20060147532-A1 Microparticles prepared using an ionic liquid AUSBORN MICHAEL 2006-07-06 US claimed
US-20050205493-A1 Ionic liquids as solvents in headspace gas chromatography NOVARTIS AG (CH) 2005-09-22 US claimed
EP-1569621-A1 MICROPARTICLES PREPARED USING AN IONIC LIQUID Novartis AG (CH) 2005-09-07 EP claimed
EP-1529205-A2 ANALYTICAL PROCESS Novartis AG (CH) 2005-05-11 EP claimed
WO-2004052340-A1 MICROPARTICLES PREPARED USING AN IONIC LIQUID NOVARTIS AG (CH) 2004-06-24 WO claimed
WO-2004013612-A2 IONIC LIQUIDS AS SOLVENTS IN HEADSPACE GAS CHROMATOGRAPHY NOVARTIS AG (CH) 2004-02-12 WO claimed
US-5994602-A IN THE PRESENCE OF A HYDROCARBYL ALUMINUM OR GALLIUM HALIDE AND A HYDROCARBYL-SUBSTITUTED IMIDAZOLIUM OR PYRIDINIUM HALIDE BP CHEMICALS LIMITED (GB) 1999-11-30 US claimed
WO-1998047616-A1 CATALYST COMPRISING A BUFFERED IONIC LIQUID AND HYDROCARBON CONVERSION PROCESS, E.G. OLIGOMERISATION BP CHEMICALS LIMITED (GB) 1998-10-29 WO claimed
EP-0693045-B1 ALKYLATION PROCESS BP CHEM INT LTD (GB) 1997-10-22 EP claimed
EP-0693045-A1 ALKYLATION PROCESS BP CHEM INT LTD (GB) 1996-01-24 EP claimed
WO-1995021872-A1 IONIC LIQUIDS BP CHEMICALS LIMITED (GB) 1995-08-17 WO claimed
WO-1995021806-A1 ALKYLATION PROCESS BP CHEMICALS LIMITED (GB) 1995-08-17 WO claimed
EP-2593403-B1 METHOD FOR PRODUCING A GEL FILM AND FILTRATION MEMBRANE PREPARED WITH THIS METHOD UNIV MONASH (AU) 2020-03-04 EP disclosed
EP-0558187-A1 Butene polymers BP Chemicals Limited (GB) 1993-09-01 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100239524-A1 MICROPARTICLES PREPARED USING AN IONIC LIQUID FIBP, MIF, CHMP4B TDP1 1587/4885TSHR 3760/4885NAPRT 4128/4885
US-20120136189-A1 BUFFERED IONIC LIQUIDS FOR OLEFIN DIMERIZATION OSBPL8, OSBP, OSBP2 TDP1 2022/4885TSHR 2589/4885NAPRT 2710/4885
US-20060147532-A1 Microparticles prepared using an ionic liquid FIBP, MIF, CHMP4B TDP1 1587/4885TSHR 3760/4885NAPRT 4128/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.