Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AXL | P30530 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.35 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.35 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1790483 | 0.78 | MAPK1 (0.43) | KMT2AALDH1A1HPGDMAPK1CYP1A2 | |
| SCHEMBL3662262 | 0.69 | KDM4E (0.46) | KMT2AALDH1A1HPGDMAPK1SMN1; SMN2 | |
| SCHEMBL11903207 | 0.69 | HSD17B10 (0.36) | KMT2AALDH1A1HSP90AA1HSP90AB1HPGD | |
| SCHEMBL4384494 | 0.68 | MAPK1 (0.46) | KMT2AALDH1A1MAPK1CYP1A2NPC1 | |
| SCHEMBL164625 | 0.68 | MAPK1 (0.46) | ALDH1A1MAPK1CYP1A2NPC1TP53 | |
| SCHEMBL1653862 | 0.68 | HSD17B10 (0.34) | KMT2AALDH1A1HSP90AA1HSP90AB1HPGD | |
| SCHEMBL30740821 | 0.68 | JAK3 (0.45) | ALDH1A1SMN1; SMN2GAAMAPTPOLB | |
| SCHEMBL13728573 | 0.67 | S1PR4 (0.36) | KMT2AALDH1A1CYP1A2NPC1RAB9A | |
| SCHEMBL15500861 | 0.66 | MAPT (0.46) | ALDH1A1MAPK1CYP1A2NPC1TP53 | |
| SCHEMBL22518516 | 0.66 | MAPK1 (0.44) | ALDH1A1MAPK1CYP1A2NPC1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2237669-A2 | CHEMICAL COMPOUNDS | Syngenta Limited (GB) | 2010-10-13 | — | — | EP | disclosed |
| WO-2009081112-A2 | CHEMICAL COMPOUNDS | SYNGENTA LIMITED (GB) | 2009-07-02 | — | — | WO | disclosed |