Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR4 | O95977 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 6/20 | 0.34 |
| ▸ | RAB9A | P51151 | 6/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14907202 | 0.76 | PIK3C3 (0.42) | KMT2AMAPTSMN1; SMN2ALDH1A1CYP1A2 | |
| SCHEMBL13728976 | 0.75 | TDP1 (0.35) | HTTNPSR1GAANPC1RAB9A | |
| SCHEMBL353627 | 0.75 | S1PR4 (0.35) | S1PR4HTTNPSR1NPC1RAB9A | |
| SCHEMBL29793641 | 0.71 | CLK1 (0.36) | RAB9AKMT2AMAPTPKMALDH1A1 | |
| SCHEMBL17660518 | 0.71 | CLK1 (0.36) | RAB9AKMT2AMAPTPKMALDH1A1 | |
| SCHEMBL18920572 | 0.70 | KMT2A (0.50) | HTTNPC1RAB9AKMT2AMAPT | |
| SCHEMBL1694938 | 0.69 | LMNA (0.41) | S1PR4GAANPC1RAB9AKMT2A | |
| SCHEMBL3577961 | 0.69 | SMN1; SMN2 (0.47) | S1PR4GAANPC1RAB9AKMT2A | |
| SCHEMBL9547540 | 0.68 | CES2 (0.39) | S1PR4NPC1RAB9AKMT2AMAPT | |
| Hydrochloric Acid SCHEMBL5352593 | 0.68 | SMN1; SMN2 (0.46) | S1PR4GAANPC1RAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012151567-A1 | PYRIMIDINONE COMPOUNDS AND METHODS FOR PREVENTING AND TREATING INFLUENZA | ST. JUDE CHILDREN'S RESEARCH HOSPITAL (US) | 2012-11-08 | — | — | WO | disclosed |