Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA3 | P07451 | 1/20 | 0.31 |
| ▸ | CA5A | P35218 | 1/20 | 0.31 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ammonia Solution, Strong SCHEMBL27881667 | 0.98 | CA3 (0.30) | CA3CA5ACA5B | |
| SCHEMBL1082749 | 0.78 | CYP3A4 (0.41) | — | |
| SCHEMBL9987847 | 0.78 | — | — | |
| SCHEMBL28427366 | 0.76 | CYP3A4 (0.39) | — | |
| SCHEMBL28761387 | 0.76 | CYP3A4 (0.39) | — | |
| SCHEMBL23746047 | 0.76 | TK1 (0.33) | — | |
| SCHEMBL29506833 | 0.76 | CYP3A4 (0.39) | — | |
| SCHEMBL11444238 | 0.76 | CYP3A4 (0.39) | — | |
| Ammonia Solution, Strong SCHEMBL11233126 | 0.76 | CYP3A4 (0.39) | — | |
| SCHEMBL10767806 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2235037-A1 | STEROID DERIVATIVES ACTING AS GLUCOCORTICOSTEROID RECEPTOR AGONISTS | AstraZeneca AB (SE) | 2010-10-06 | — | — | EP | disclosed |
| WO-2009082342-A1 | STEROID DERIVATIVES ACTING AS GLUCOCORTICOSTEROID RECEPTOR AGONISTS | ASTRAZENECA AB (SE) | 2009-07-02 | — | — | WO | disclosed |