Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 7/20 | 0.75 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.75 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.75 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4909383 | 0.91 | TSHR (0.82) | TSHRALDH1A1CYP3A4KDM4ETDP1 | |
| SCHEMBL4914939 | 0.89 | TSHR (0.78) | TSHRALDH1A1CYP3A4KDM4ETDP1 | |
| SCHEMBL172289 | 0.89 | TSHR (0.78) | TSHRALDH1A1CYP3A4KDM4ETDP1 | |
| SCHEMBL2404148 | 0.89 | TSHR (0.78) | TSHRALDH1A1CYP3A4KDM4ETDP1 | |
| SCHEMBL4913063 | 0.89 | TSHR (0.78) | TSHRALDH1A1CYP3A4KDM4ETDP1 | |
| SCHEMBL5034731 | 0.89 | TSHR (0.78) | TSHRALDH1A1CYP3A4KDM4ETDP1 | |
| SCHEMBL172288 | 0.88 | TSHR (0.69) | TSHRALDH1A1CYP3A4KDM4ETDP1 | |
| SCHEMBL7785935 | 0.87 | ALDH1A1 (0.75) | TSHRALDH1A1CYP3A4KDM4ETDP1 | |
| Hydrochloric Acid SCHEMBL11121262 | 0.87 | CYP3A4 (0.75) | TSHRALDH1A1CYP3A4KDM4ETDP1 | |
| SCHEMBL23611735 | 0.86 | TSHR (1.00) | TSHRALDH1A1CYP3A4KDM4ETDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2242786-A1 | NOVEL COMPOSITIONS AND METHODS INCLUDING ALTERNATING COPOLYMERS COMPRISING DITHIENOPYRROLE UNITS | Plextronics, Inc. (US) | 2010-10-27 | — | — | EP | disclosed |
| WO-2009103030-A1 | NOVEL COMPOSITIONS AND METHODS INCLUDING ALTERNATING COPOLYMERS COMPRISING DITHIENOPYRROLE UNITS | PLEXTRONICS, INC. (US) | 2009-08-20 | — | — | WO | disclosed |