Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 11/20 | 0.65 |
| ▸ | ACHE | P22303 | 7/20 | 0.55 |
| ▸ | BCHE | P06276 | 4/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17156985 | 0.88 | LTA4H (0.66) | LTA4HACHEBCHE | |
| SCHEMBL17156991 | 0.87 | LTA4H (0.59) | LTA4HACHEBCHE | |
| SCHEMBL2788674 | 0.84 | LTA4H (0.49) | LTA4HACHEBCHE | |
| SCHEMBL2787278 | 0.83 | LTA4H (0.89) | LTA4H | |
| Hydrochloric Acid SCHEMBL9772589 | 0.83 | LTA4H (0.66) | LTA4H | |
| SCHEMBL17156982 | 0.82 | LTA4H (0.54) | LTA4HACHEBCHE | |
| Hydrochloric Acid SCHEMBL9157294 | 0.82 | LTA4H (0.86) | LTA4HACHEBCHE | |
| SCHEMBL2422195 | 0.81 | KDM4E (0.57) | — | |
| SCHEMBL4531624 | 0.79 | LTA4H (1.00) | LTA4H | |
| SCHEMBL17156989 | 0.79 | ACHE (0.47) | LTA4HACHEBCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2240501-B1 | HYDROXY-BISPHOSPHONIC ACID DERIVATIVES AS VECTOR FOR TARGETING BONE TISSUE | UNIV NANTES (FR) | 2015-10-14 | — | — | EP | disclosed |
| EP-2240501-A1 | HYDROXY-BISPHOSPHONIC ACID DERIVATIVES AS VECTOR FOR TARGETING BONE TISSUE | Université de Nantes (FR) | 2010-10-20 | — | — | EP | disclosed |
| WO-2009083614-A1 | HYDROXY-BISPHOSPHONIC ACID DERIVATIVES AS VECTOR FOR TARGETING BONE TISSUE | UNIVERSITE DE NANTES (FR) | 2009-07-09 | — | — | WO | disclosed |