Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STK10 | O94804 | 4/20 | 0.35 |
| ▸ | SLK | Q9H2G2 | 4/20 | 0.35 |
| ▸ | SNCA | P37840 | 1/20 | 0.34 |
| ▸ | GSK3B | P49841 | 7/20 | 0.32 |
| ▸ | BRAF | P15056 | 2/20 | 0.32 |
| ▸ | NSD2 | O96028 | 1/20 | 0.31 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.31 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.31 |
| ▸ | CASP7 | P55210 | 1/20 | 0.31 |
| ▸ | CASP6 | P55212 | 1/20 | 0.31 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | GNG2 | P59768 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Lithium Ion SCHEMBL16937435 | 0.87 | STK10 (0.33) | STK10SLK | |
| SCHEMBL3678283 | 0.83 | SNCA (0.35) | STK10SLKSNCAGSK3BBRAF | |
| SCHEMBL170997 | 0.70 | ALDH1A1 (0.41) | NSD2DUSP3PTPN5CASP6PTPN11 | |
| SCHEMBL5766206 | 0.62 | CDK4 (0.42) | GSK3BCASP7CASP6CASP3 | |
| SCHEMBL7034713 | 0.62 | TNNI3K (0.39) | ALDH1A1MAPK1HSD17B10 | |
| SCHEMBL6865288 | 0.62 | SNCA (0.72) | SNCANSD2DUSP3PTPN5CASP7 | |
| SCHEMBL10972252 | 0.62 | CA1 (0.50) | SNCAALDH1A1HSD17B10 | |
| SCHEMBL7838585 | 0.61 | CA1 (0.42) | SNCAALDH1A1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL9717494 | 0.61 | SNCA (0.76) | SNCANSD2DUSP3PTPN5CASP7 | |
| SCHEMBL54845 | 0.61 | TSHR (0.50) | ALDH1A1MAPK1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6600017-B1 | Peptide for use in diagnosing alzheimer's disease | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2003-07-29 | — | — | US | claimed |
| EP-2913402-B1 | Retrovirus detection | TOCAGEN INC (US) | 2017-10-18 | — | — | EP | disclosed |
| US-9663834-B2 | Retrovirus detection | TOCAGEN INC. (US) | 2017-05-30 | — | — | US | disclosed |
| EP-2913402-A1 | Retrovirus detection | Tocagen Inc. (US) | 2015-09-02 | — | — | EP | disclosed |
| US-20130266931-A1 | RETROVIRUS DETECTION | TOCAGEN INC. (US) | 2013-10-10 | — | — | US | disclosed |
| EP-2580325-A2 | RETROVIRUS DETECTION | Tocagen Inc. (US) | 2013-04-17 | — | — | EP | disclosed |
| WO-2012009711-A2 | RETROVIRUS DETECTION | TOCAGEN INC. (US) | 2012-01-19 | — | — | WO | disclosed |
| US-20070238096-A1 | Hybrid energy transfer for nucleic acid detection | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2007-10-11 | — | — | US | disclosed |
| WO-2007103558-A2 | HYBRID ENERGY TRANSFER FOR NUCLEIC ACID DETECTION | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2007-09-13 | — | — | WO | disclosed |
| US-6770448-B2 | CONTACTING A SAMPLE WITH AN AGGREGATING AMYLOID A BETA PEPTIDE TO WHICH IS COVALENTLY BONDED A FLUORESCENT LABEL AND DETECTING THE FLUORESCENT LABEL IN ASSOCIATION WITH SUCH SAMPLE AS AN INDICATION OF AN AMYLOID AGGREGATE | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2004-08-03 | — | — | US | disclosed |
| US-6600017-B1 | Peptide for use in diagnosing alzheimer's disease | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2003-07-29 | — | — | US | disclosed |