Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | APAF1 | O14727 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | G6PD | P11413 | 1/20 | 0.43 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.43 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.43 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.43 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.43 |
| ▸ | ALKBH1 | Q13686 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.39 |
| ▸ | BACE1 | P56817 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL366360 | 0.90 | FFAR1 (0.47) | ELANEMAOBMAPTKDM4EMEN1 | |
| SCHEMBL364784 | 0.89 | KDM4E (0.47) | ELANEMAOBMAPTKDM4EMEN1 | |
| SCHEMBL366971 | 0.89 | MAPT (0.48) | MAPTKDM4EMEN1APAF1ALDH1A1 | |
| SCHEMBL364674 | 0.87 | KDM4E (0.48) | ELANERAB9AMAOBMAPTKDM4E | |
| SCHEMBL4477445 | 0.86 | RXRA (0.50) | RAB9AMAPTKDM4EMEN1APAF1 | |
| SCHEMBL367033 | 0.85 | KMT2A (0.62) | ELANERAB9AMAOBMAPTKDM4E | |
| SCHEMBL364519 | 0.84 | MAPT (0.43) | ELANERAB9AMAOBMAPTKDM4E | |
| SCHEMBL365359 | 0.83 | ALDH1A1 (0.47) | ELANEMAPTKDM4EMEN1APAF1 | |
| SCHEMBL364182 | 0.82 | MAOB (0.46) | ELANEMAOBMAPTKDM4EMEN1 | |
| SCHEMBL365355 | 0.82 | ALDH1A1 (0.44) | ELANERAB9AMAPTKDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012007007-A1 | INHIBITORS OF HDME | EPITHERAPEUTICS APS (DK) | 2012-01-19 | — | — | WO | claimed |
| WO-2012007007-A1 | INHIBITORS OF HDME | EPITHERAPEUTICS APS (DK) | 2012-01-19 | — | — | WO | disclosed |