Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.45 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14916109 | 0.78 | ELANE (0.43) | ALDH1A1KDM4ETSHRHSD17B10SMN1; SMN2 | |
| SCHEMBL3715412 | 0.74 | SLC18A3 (0.40) | ALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL2490943 | 0.72 | TP53 (0.67) | ALDH1A1KDM4EKMT2AHSD17B10SMN1; SMN2 | |
| SCHEMBL29427445 | 0.72 | GAA (0.55) | ALDH1A1KDM4ETSHRMEN1KMT2A | |
| SCHEMBL31602755 | 0.72 | HSD17B10 (0.67) | ALDH1A1KDM4ETSHRMEN1KMT2A | |
| SCHEMBL6015870 | 0.72 | ALDH1A1 (0.54) | ALDH1A1KDM4ETSHRMEN1KMT2A | |
| SCHEMBL3626813 | 0.72 | HSD17B10 (0.67) | ALDH1A1KDM4ETSHRMEN1KMT2A | |
| SCHEMBL13791090 | 0.71 | GAA (0.54) | ALDH1A1KDM4ETSHRMEN1KMT2A | |
| SCHEMBL15623056 | 0.70 | GAA (0.56) | ALDH1A1KDM4ETSHRMEN1KMT2A | |
| SCHEMBL151122 | 0.69 | KDM4E (0.71) | ALDH1A1KDM4ETSHRMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2212329-B1 | NOVEL COMPOUNDS OF REVERSE TURN MIMETICS AND THE USE THEREOF (1) | CHOONGWAE PHARMA CORP (KR) | 2014-07-30 | — | — | EP | claimed |
| EP-2212329-A2 | NOVEL COMPOUNDS OF REVERSE TURN MIMETICS AND THE USE THEREOF (1) | Choongwae Pharma Corporation (KR) | 2010-08-04 | — | — | EP | claimed |
| WO-2009051399-A2 | NOVEL COMPOUNDS OF REVERSE TURN MIMETICS AND THE USE THEREOF (1) | CHOONGWAE PHARMA CORPORATION (KR) | 2009-04-23 | — | — | WO | claimed |
| EP-2212329-B1 | NOVEL COMPOUNDS OF REVERSE TURN MIMETICS AND THE USE THEREOF (1) | CHOONGWAE PHARMA CORP (KR) | 2014-07-30 | — | — | EP | disclosed |