SCHEMBL3663640

SCHEMBL3663640

Cn1c(-c2ccccc2)cc2onc(-c3ccccc3)c2c1=O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 7/20 1.00
RAB9A P51151 6/20 1.00
CASP3 P42574 1/20 1.00
SENP8 Q96LD8 1/20 1.00
SENP7 Q9BQF6 1/20 1.00
SENP6 Q9GZR1 1/20 1.00
NR4A2 P43354 3/20 0.88
MITF O75030 1/20 0.88
TSHR P16473 1/20 0.76
DCTPP1 Q9H773 1/20 0.76

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5532304 0.97 NPC1 (0.95) NPC1RAB9ACASP3SENP8SENP7
SCHEMBL6069179 0.94 NR4A2 (1.00) NPC1RAB9ACASP3SENP8SENP7
SCHEMBL2482452 0.94 NR4A2 (1.00) NPC1RAB9ACASP3SENP8SENP7
SCHEMBL11409495 0.94 NPC1 (1.00) NPC1RAB9ACASP3SENP8SENP7
SCHEMBL2482092 0.94 NPC1 (1.00) NPC1RAB9ACASP3SENP8SENP7
SCHEMBL11420874 0.92 NPC1 (0.85) NPC1RAB9ACASP3SENP8SENP7
SCHEMBL11413840 0.92 NPC1 (0.85) NPC1RAB9ACASP3SENP8SENP7
SCHEMBL11406007 0.92 NPC1 (0.85) NPC1RAB9ACASP3SENP8SENP7
SCHEMBL11420574 0.92 NPC1 (0.85) NPC1RAB9ACASP3SENP8SENP7
SCHEMBL2485014 0.90 NR4A2 (0.83) NPC1RAB9ACASP3SENP8SENP7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 405 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250360137-A1 ENHANCEMENT OF THE EFFICACY OF SEROTONERGIC PSYCHEDELIC DRUGS IN THE TREATMENT OR PREVENTION OF CERTAIN NEUROPSYCHIATRIC DISORDERS THROUGH INHIBITION OF TYPE-9 PHOSPHODIESTERASES FREEDOM BIOSCIENCES INC (US) 2025-11-27 US claimed
EP-4618980-A1 ENHANCEMENT OF THE EFFICACY OF SEROTONERGIC PSYCHEDELIC DRUGS IN THE TREATMENT OR PREVENTION OF CERTAIN NEUROPSYCHIATRIC DISORDERS THROUGH INHIBITION OF TYPE-9 PHOSPHODIESTERASES Freedom Biosciences, Inc. (US) 2025-09-24 EP claimed
CN-120082056-A Zirconium-based metal organic framework material and preparation method and application thereof 南京工业大学 2025-06-03 CN claimed
US-20250136548-A1 FUNCTIONALIZED ALKYLAMINES TERRAN BIOSCIENCES INC (US) 2025-05-01 US claimed
CN-222600093-U Internet of things monitoring host 深圳市宇泰科技有限公司 2025-03-11 CN claimed
CN-118834396-A Metal-organic framework material suitable for propylene-propane adsorption separation and preparation method thereof 南开大学 2024-10-25 CN claimed
CN-117952196-B TBM tunneling parameter intelligent auxiliary decision-making system and method based on data-knowledge dual driving 江河安澜工程咨询有限公司 2024-08-13 CN claimed
EP-3805238-B1 NOVEL METAL-ORGANIC FRAMEWORK HAVING POROUS STRUCTURE FORMED FROM ZIRCONIUM CLUSTER SECONDARY BUILDING UNIT AND MULTI-BINDING LINKER KOREA RES INST CHEMICAL TECH (KR) 2024-07-03 EP claimed
WO-2024137858-A2 METHODS AND COMPOSITIONS FOR ASSESSING COLORECTAL CANCER SINGLERA GENOMICS INC. (US) 2024-06-27 WO claimed
CN-221177728-U Ethernet interface interconnection circuit 成都天奥测控技术有限公司 2024-06-18 CN claimed
CN-117992310-A Exception handling method for monitoring Tomcat 暨南大学附属顺德医院(佛山市顺德区第二人民医院、佛山市顺德区冯尧敬纪念医院) 2024-05-07 CN claimed
CN-117952196-A TBM tunneling parameter intelligent auxiliary decision-making system and method based on data-knowledge dual driving 江河安澜工程咨询有限公司 2024-04-30 CN claimed
CN-117812484-A Vehicle-mounted hundred megaEthernet bifurcation circuit 上海创时汽车科技有限公司 2024-04-02 CN claimed
CN-116636218-A Video encoding and decoding using multi-directional intra-prediction 北京达佳互联信息技术有限公司 2023-08-22 CN claimed
CN-116558729-A Mould and method for checking air tightness of MDIP shell glass insulator 中国电子科技集团公司第十三研究所 2023-08-08 CN claimed
WO-2023141595-A2 FUNCTIONALIZED ALKYLAMINES TERRAN BIOSCIENCES, INC. (US) 2023-07-27 WO claimed
WO-2022221942-A1 PREVENTION OF DRUG DIVERSION BETTERLIFE PHARMA INC. (CA) 2022-10-27 WO claimed
CN-113547997-B Vehicle-mounted display device and system based on vehicle-mounted Ethernet interface 东风汽车集团股份有限公司 2022-09-23 CN claimed
CN-114362114-A Interface surge protection circuit of Ethernet physical layer chip 裕太微电子股份有限公司 2022-04-15 CN claimed
EP-1418912-B1 ISOXAZOLOPYRIDINONES NOVARTIS AG (CH) 2007-02-28 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250360137-A1 ENHANCEMENT OF THE EFFICACY OF SEROTONERGIC PSYCHEDELIC DRUGS IN THE TREATMENT OR PREVENTION OF CERTAIN NEUROPSYCHIATRIC DISORDERS THROUGH INHIBITION OF TYPE-9 PHOSPHODIESTERASES PDE9A, PDE3A, PDE2A NPC1 1521/4885RAB9A 185/4885CASP3 1700/4885
US-20250136548-A1 FUNCTIONALIZED ALKYLAMINES BDNF, HTR2A, NTRK2 NPC1 2185/4885RAB9A 1320/4885CASP3 1624/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.