Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | AR | P10275 | 5/20 | 0.37 |
| ▸ | IDO1 | P14902 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | KIF11 | P52732 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CES1 | P23141 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29957886 | 0.80 | MPL (0.37) | ALDH1A1POLBTDP1L3MBTL1IDO1 | |
| SCHEMBL29956247 | 0.76 | TDP1 (0.44) | ALDH1A1TDP1TSHRKIF11 | |
| SCHEMBL261312 | 0.76 | ALDH1A1 (0.39) | ALDH1A1POLBTDP1L3MBTL1AR | |
| SCHEMBL420138 | 0.76 | TDP1 (0.44) | ALDH1A1TDP1TSHRKIF11 | |
| Fluoride Ion SCHEMBL11774111 | 0.74 | ALDH1A1 (0.38) | ALDH1A1POLBTDP1L3MBTL1AR | |
| Hydrochloric Acid SCHEMBL7120447 | 0.74 | ALDH1A1 (0.42) | ALDH1A1POLBTDP1L3MBTL1IDO1 | |
| Hydrochloric Acid SCHEMBL18936435 | 0.74 | ALDH1A1 (0.38) | ALDH1A1POLBTDP1L3MBTL1AR | |
| Hydrochloric Acid SCHEMBL9659775 | 0.74 | ALDH1A1 (0.42) | ALDH1A1POLBTDP1L3MBTL1AR | |
| SCHEMBL63469 | 0.73 | ALDH1A1 (0.52) | ALDH1A1POLBTDP1L3MBTL1IDO1 | |
| SCHEMBL29441997 | 0.73 | ALDH1A1 (0.52) | ALDH1A1POLBTDP1L3MBTL1IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |
| EP-2238103-A1 | NOVEL N-(2-AMINO-PHENYL)-AMIDE DERIVATIVES | F. Hoffmann-La Roche AG (CH) | 2010-10-13 | — | — | EP | disclosed |
| WO-2009095324-A1 | NOVEL N-(2-AMINO-PHENYL)-AMIDE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2009-08-06 | — | — | WO | disclosed |