Sugi Predict

Sugi Predict / Compounds / SCHEMBL261312

SCHEMBL261312

SCHEMBL261312

N#[N+]c1ccccc1C(F)(F)F

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 3/20 0.39
▸ TDP1 Q9NUW8 2/20 0.39
▸ POLB P06746 1/20 0.39
▸ L3MBTL1 Q9Y468 1/20 0.39
▸ IDO1 P14902 2/20 0.36
▸ LMNA P02545 2/20 0.35
▸ GAA P10253 1/20 0.35
▸ TSHR P16473 1/20 0.35
▸ HSD11B1 P28845 1/20 0.34
▸ NFKB1 P19838 1/20 0.34
▸ KIF11 P52732 1/20 0.34
▸ AR P10275 1/20 0.34
▸ HTR2C P28335 2/20 0.33
▸ MEN1 O00255 2/20 0.33
▸ KMT2A Q03164 2/20 0.33
▸ CES1 P23141 1/20 0.33
▸ CUL4A Q13619 1/20 0.33
▸ CYP1A2 P05177 1/20 0.32
▸ CYP3A4 P08684 1/20 0.32
▸ CYP2D6 P10635 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Fluoride Ion SCHEMBL11774111 0.98 ALDH1A1 (0.38) ALDH1A1TDP1POLBL3MBTL1IDO1
Hydrochloric Acid SCHEMBL9659775 0.98 ALDH1A1 (0.42) ALDH1A1TDP1POLBL3MBTL1IDO1
Hydrochloric Acid SCHEMBL18936435 0.98 ALDH1A1 (0.38) ALDH1A1TDP1POLBL3MBTL1IDO1
SCHEMBL260225 0.94 LMNA (0.36) ALDH1A1TDP1POLBL3MBTL1IDO1
SCHEMBL9814307 0.90 ALDH1A1 (0.37) ALDH1A1TDP1POLBL3MBTL1IDO1
SCHEMBL22028677 0.76 TDP1 (0.44) ALDH1A1TDP1TSHRKIF11
SCHEMBL3663843 0.76 ALDH1A1 (0.39) ALDH1A1TDP1POLBL3MBTL1IDO1
Hydrochloric Acid SCHEMBL7120447 0.74 ALDH1A1 (0.42) ALDH1A1TDP1POLBL3MBTL1IDO1
SCHEMBL11526486 0.74 TAS2R14 (0.38) HSD11B1ARCES1NOTUM
SCHEMBL5573854 0.74 ALDH1A1 (0.39) ALDH1A1TDP1TSHRKIF11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3178811-B1 A PROCESS FOR THE SYNTHESIS OF SULFONES AND SULFONAMIDES COMMISSARIAT ENERGIE ATOMIQUE (FR) 2018-10-31 — — EP claimed
US-7846383-B2 Lateral flow assay device and absorbent article containing same KIMBERLY-CLARK WORLDWIDE, INC. (US) 2010-12-07 — — US claimed
US-20080145945-A1 Lateral flow assay device and absorbent article containing same KIMBERLY-CLARK WORLDWIDE, INC. 2008-06-19 — — US claimed
CN-115559119-B Multifunctional super-hydrophobic fabric and preparation method thereof 苏州大学 2024-07-05 — — CN disclosed
CN-115559119-A Multifunctional super-hydrophobic fabric and preparation method thereof 苏州大学 2023-01-03 — — CN disclosed
CN-113845405-B Method for continuously synthesizing diflufenican intermediate m-trifluoromethylphenol 江苏快达农化股份有限公司 2022-12-13 — — CN disclosed
CN-110818533-B Preparation method of m-trifluoromethylphenol 浙江巍华新材料股份有限公司 2022-04-12 — — CN disclosed
CN-113845405-A Method for continuously synthesizing diflufenican intermediate m-trifluoromethylaniline 江苏快达农化股份有限公司 2021-12-28 — — CN disclosed
CN-214051584-U Diazonium salt hydrolysis reaction system 上海惠和化德生物科技有限公司 2021-08-27 — — CN disclosed
CN-110818533-A Preparation method of m-trifluoromethylphenol 浙江巍华新材料股份有限公司 2020-02-21 — — CN disclosed
US-8133549-B2 Method for modifying insulating or semi-conductive surfaces, and resulting products ALCHIMER (FR) 2012-03-13 — — US disclosed
US-20060014809-A1 Substituted triazoles as modulators of PPAR and methods of their preparation METABOLEX, INC. (US) 2006-01-19 — — US disclosed
US-20060014785-A1 BICYCLIC, SUBSTITUTED TRIAZOLES AS MODULATORS OF PPAR AND METHODS OF THEIR PREPARATION METABOLEX, INC. (US) 2006-01-19 — — US disclosed
WO-2005115383-A2 SUBSTITUTED TRIAZOLES AS MODULATORS OF PPAR AND METHODS OF THEIR PREPARATION METABOLEX, INC. (US) 2005-12-08 — — WO disclosed
WO-2005115384-A2 BICYCLIC, SUBSTITUTED TRIAZOLES AS MODULATORS OF PPAR AND METHODS OF THEIR PREPARATION METABOLEX, INC. (US) 2005-12-08 — — WO disclosed
EP-0477105-B1 Testing device TERUMO CORP (JP) 1994-12-28 — — EP disclosed
US-5244631-A Platelike stick composed of water-disintegratable layer with superposed water-soluble layer and multiplicity of minute pieces of water-insoluble material, detecting function part deposited on stick surface TERUMO KABUSHIKI KAISHA (JP) 1993-09-14 — — US disclosed
EP-0477105-A1 Testing device TERUMO KABUSHIKI KAISHA (JP) 1992-03-25 — — EP disclosed
EP-0016132-A1 NEW SUBSTITUTED PHENYLUREA HERBICIDE RHONE-POULENC AGROCHIMIE (FR) 1980-10-01 — — EP disclosed
WO-1980000344-A1 NEW SUBSTITUTED PHENYLUREA HERBICIDE RHONE POULENC AGROCHIMIE (FR) 1980-03-06 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060014809-A1 Substituted triazoles as modulators of PPAR and methods of their preparation PPARG, PPARD, GPR119 ALDH1A1 2436/4885TDP1 1868/4885POLB 3029/4885
US-20060014785-A1 BICYCLIC, SUBSTITUTED TRIAZOLES AS MODULATORS OF PPAR AND METHODS OF THEIR PREPARATION PPARG, PPARD, GPR119 ALDH1A1 2102/4885TDP1 2180/4885POLB 2930/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.