Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 7/20 | 0.55 |
| ▸ | LMNA | P02545 | 4/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.55 |
| ▸ | STAT3 | P40763 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Linalyl Acetate SCHEMBL27789241 | 0.96 | ALOX15 (0.59) | ALOX15LMNACYP3A4STAT3MAPK1 | |
| Linalool SCHEMBL29113952 | 0.89 | LMNA (0.58) | ALOX15LMNACYP3A4STAT3MAPK1 | |
| Linalool SCHEMBL5801612 | 0.89 | LMNA (0.58) | ALOX15LMNACYP3A4STAT3MAPK1 | |
| Linalool SCHEMBL7633462 | 0.89 | LMNA (0.58) | ALOX15LMNACYP3A4STAT3MAPK1 | |
| Linalyl Acetate SCHEMBL28080375 | 0.88 | ALOX15 (0.44) | ALOX15LMNACYP3A4STAT3MAPK1 | |
| (-)-Limonene SCHEMBL8033433 | 0.84 | LMNA (0.50) | ALOX15LMNACYP3A4STAT3MAPK1 | |
| Linalyl Acetate SCHEMBL28096246 | 0.82 | ALOX15 (0.68) | ALOX15LMNACYP3A4STAT3MAPK1 | |
| Linalool SCHEMBL2931642 | 0.80 | ALOX15 (0.44) | ALOX15LMNACYP3A4STAT3MAPK1 | |
| Linalyl Acetate SCHEMBL5773882 | 0.80 | ALOX15 (0.67) | ALOX15LMNACYP3A4STAT3MAPK1 | |
| (-)-Limonene SCHEMBL27845657 | 0.78 | LMNA (0.50) | ALOX15LMNACYP3A4STAT3MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2242498-A2 | SYNERGISTIC ANTIPARASITIC COMPOSITIONS AND SCREENING METHODS | Tyratech, Inc. (US) | 2010-10-27 | — | — | EP | disclosed |
| WO-2009086471-A2 | SYNERGISTIC ANTIPARASITIC COMPOSITIONS AND SCREENING METHODS | TYRATECH, INC. (US) | 2009-07-09 | — | — | WO | disclosed |