Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | RAD52 | P43351 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | PHLPP2 | Q6ZVD8 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | POLR1A | O95602 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | HTR1D | P28221 | 1/20 | 0.38 |
| ▸ | HTR1B | P28222 | 1/20 | 0.38 |
| ▸ | HTR1F | P30939 | 1/20 | 0.38 |
| ▸ | HTR7 | P34969 | 1/20 | 0.38 |
| ▸ | HTR6 | P50406 | 1/20 | 0.38 |
| ▸ | BCHE | P06276 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL364887 | 0.88 | ALDH1A1 (0.52) | ALDH1A1TDP1MEN1KMT2ARAD52 | |
| SCHEMBL366312 | 0.88 | ALDH1A1 (0.52) | ALDH1A1TDP1MEN1KMT2ARAD52 | |
| SCHEMBL365839 | 0.87 | ALDH1A1 (0.54) | ALDH1A1TDP1MEN1KMT2ARAD52 | |
| SCHEMBL365801 | 0.87 | ALDH1A1 (0.51) | ALDH1A1TDP1MEN1KMT2ARAD52 | |
| SCHEMBL365400 | 0.86 | ELANE (0.47) | ALDH1A1TDP1MEN1KMT2AMAPT | |
| SCHEMBL365411 | 0.86 | ALDH1A1 (0.53) | ALDH1A1TDP1MEN1KMT2ARAD52 | |
| SCHEMBL366836 | 0.86 | ALDH1A1 (0.50) | ALDH1A1TDP1MEN1KMT2APOLB | |
| SCHEMBL365533 | 0.85 | ALDH1A1 (0.49) | ALDH1A1TDP1MEN1KMT2ARAD52 | |
| SCHEMBL367114 | 0.85 | ALDH1A1 (0.49) | ALDH1A1TDP1MEN1KMT2ARAD52 | |
| SCHEMBL364996 | 0.85 | ALDH1A1 (0.49) | ALDH1A1TDP1MEN1KMT2ARAD52 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012007007-A1 | INHIBITORS OF HDME | EPITHERAPEUTICS APS (DK) | 2012-01-19 | — | — | WO | disclosed |