Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | NOS3 | P29474 | 4/20 | 0.38 |
| ▸ | NOS1 | P29475 | 3/20 | 0.38 |
| ▸ | NOS2 | P35228 | 3/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | INMT | O95050 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9835844 | 0.81 | — | — | |
| SCHEMBL142379 | 0.81 | — | — | |
| SCHEMBL329231 | 0.79 | — | — | |
| Hydrochloric Acid SCHEMBL14844794 | 0.77 | NOS3 (0.48) | TP53RAB9ANOS3NOS1NOS2 | |
| SCHEMBL4674692 | 0.74 | — | — | |
| SCHEMBL883443 | 0.74 | — | — | |
| SCHEMBL2134321 | 0.74 | — | — | |
| SCHEMBL12762365 | 0.72 | NOS3 (0.38) | TP53RAB9ANOS3NOS1NOS2 | |
| SCHEMBL444695 | 0.72 | — | — | |
| SCHEMBL14398018 | 0.72 | HPGD (0.42) | TP53RAB9ANOS3NOS1NOS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2235091-B1 | METHOD FOR PRODUCING ISOCYANATE-TERMINATED SILOXANES | WACKER CHEMIE AG (DE) | 2012-11-07 | — | — | EP | disclosed |
| EP-2235091-A1 | METHOD FOR PRODUCING ISOCYANATE-TERMINATED SILOXANES | Wacker Chemie AG (DE) | 2010-10-06 | — | — | EP | disclosed |
| WO-2009092665-A1 | METHOD FOR PRODUCING ISOCYANATE-TERMINATED SILOXANES | WACKER CHEMIE AG (DE) | 2009-07-30 | — | — | WO | disclosed |