Known targets — ChEMBL curated mechanism
CHRM1DRD2DRD3DRD4HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR2APDE3ASIGMAR1
The experimentally established mechanism targets of Tetrylammonium. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 known ✓ | P11229 | 2/20 | 0.36 |
| ▸ | HTR2A known ✓ | P28223 | 1/20 | 0.36 |
| ▸ | HRH1 known ✓ | P35367 | 1/20 | 0.36 |
| ▸ | DRD3 known ✓ | P35462 | 1/20 | 0.36 |
| ▸ | HDAC1 known ✓ | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC2 known ✓ | Q92769 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.61 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | KCNA1 | Q09470 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.36 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Lactic Acid SCHEMBL5569774 | 0.83 | TP53 (0.61) | TP53TSHRCHRM1CHRM3AKR1A1 | |
| Tetrylammonium SCHEMBL5874499 | 0.83 | TSHR (0.44) | TP53TSHRNFKB1KCNA1KDM4E | |
| Lactic Acid SCHEMBL27546261 | 0.82 | TP53 (0.69) | TP53TSHRCHRM1CHRM3AKR1A1 | |
| Lactic Acid SCHEMBL27721040 | 0.82 | — | — | |
| Lactic Acid SCHEMBL28099744 | 0.82 | — | — | |
| Tetrylammonium SCHEMBL28424947 | 0.81 | SLC7A5 (0.42) | TP53TSHRNFKB1KCNA1KDM4E | |
| Tetrylammonium SCHEMBL36648 | 0.81 | TSHR (0.42) | TP53TSHRNFKB1KCNA1KDM4E | |
| Lactic Acid SCHEMBL5573666 | 0.81 | TP53 (0.58) | TP53CHRM1CHRM3AKR1A1HTR2A | |
| Lactic Acid SCHEMBL3928098 | 0.79 | — | — | |
| Lactic Acid SCHEMBL1501503 | 0.79 | TP53 (0.73) | TP53CHRM1CHRM3AKR1A1HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 58 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115321585-A | Washing process of indium hydroxide | 先导薄膜材料有限公司 | 2022-11-11 | — | — | CN | claimed |
| CN-111653767-B | Washing process and preparation method of high-nickel polycrystalline ternary cathode material | 乳源东阳光磁性材料有限公司 | 2021-10-01 | — | — | CN | claimed |
| CN-109876601-B | Process method for absorbing sulfur dioxide in flue gas by functionalized ionic liquid and regenerating by Claus reaction at low temperature | 北京化工大学 | 2020-10-02 | — | — | CN | claimed |
| CN-111653767-A | Washing process and preparation method of high-nickel polycrystalline ternary cathode material | 乳源东阳光磁性材料有限公司 | 2020-09-11 | — | — | CN | claimed |
| CN-110585860-A | Low-energy-consumption regenerated absorbent and method for absorbing sulfur dioxide in flue gas by using same | 太原师范学院 | 2019-12-20 | — | — | CN | claimed |
| US-20120004268-A1 | INSECTICIDAL COMPOSITIONS COMPRISING CYCLIC CARBONYLAMIDINES | BAYER CROPSCIENCE AG (DE) | 2012-01-05 | — | — | US | claimed |
| CN-120118300-A | Polycarbonate copolymer and preparation method and application thereof | 华东理工大学 | 2025-06-10 | — | — | CN | disclosed |
| WO-2025000629-A1 | PREPARATION METHOD FOR AND USE OF IONIC-LIQUID-MODIFIED CERIUM DIOXIDE CATALYST | 中国科学院过程工程研究所 | 2025-01-02 | — | — | WO | disclosed |
| CN-118344595-A | Polydimethylsiloxane-containing bio-based polycarbonate copolymer and preparation method thereof | 中国科学院成都有机化学有限公司 | 2024-07-16 | — | — | CN | disclosed |
| CN-118255975-A | Light-responsive polycarbonate copolymer and preparation method thereof | 中国石油天然气股份有限公司 | 2024-06-28 | — | — | CN | disclosed |
| CN-117658802-A | Method for preparing lactate by catalyzing alcoholysis of polylactic acid by ionic liquid | 中国科学院化学研究所 | 2024-03-08 | — | — | CN | disclosed |
| CN-117658794-A | Method for preparing lactic acid by catalyzing polylactic acid hydrolysis through ionic liquid | 中国科学院化学研究所 | 2024-03-08 | — | — | CN | disclosed |
| CN-117623968-A | Method for preparing N-substituted lactamide by catalyzing polylactic acid aminolysis with ionic liquid | 中国科学院化学研究所 | 2024-03-01 | — | — | CN | disclosed |
| US-20090093544-A1 | INSECTICIDAL COMPOSITIONS HAVING IMPROVED EFFECT | BAYER CROPSCIENCE AG (DE) | 2009-04-09 | — | — | US | disclosed |
| CN-101370382-A | Insecticide compounds with improved effect | BAYER CROPSCIENCE AG (DE) | 2009-02-18 | — | — | CN | disclosed |
| US-20080319081-A1 | Insecticidal Compositions Having Improved Effect | BAYER CROPSCIENCE AG (DE) | 2008-12-25 | — | — | US | disclosed |
| US-20070135565-A1 | COMPOSITION FOR FORMING POROUS FILM, POROUS FILM AND METHOD FOR FORMING THE SAME, INTERLEVEL INSULATOR FILM, AND SEMICONDUCTOR DEVICE | MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) | 2007-06-14 | — | — | US | disclosed |
| US-7132473-B2 | Composition for forming porous film, porous film and method for forming the same, interlevel insulator film, and semiconductor device | MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) | 2006-11-07 | — | — | US | disclosed |
| EP-1568744-A1 | COMPOSITION FOR POROUS FILM FORMATION, POROUS FILM, PROCESS FOR PRODUCING THE SAME, INTERLAYER INSULATION FILM AND SEMICONDUCTOR DEVICE | MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) | 2005-08-31 | — | — | EP | disclosed |
| US-20040219372-A1 | Composition for forming porous film, porous film and method for forming the same, interlevel insulator film, and semiconductor device | MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. | 2004-11-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080319081-A1 | Insecticidal Compositions Having Improved Effect | PPA1, PTEN, PPM1G | CHRM1 3941/4885HTR2A 4679/4885HRH1 4412/4885 |
| US-20090093544-A1 | INSECTICIDAL COMPOSITIONS HAVING IMPROVED EFFECT | DDT, PTEN, PPA1 | CHRM1 2912/4885HTR2A 4603/4885HRH1 4115/4885 |
| US-20120004268-A1 | INSECTICIDAL COMPOSITIONS COMPRISING CYCLIC CARBONYLAMIDINES | DDT, PRMT9, PNISR | CHRM1 38/4885HTR2A 4139/4885HRH1 221/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.