Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | PAX8 | Q06710 | 2/20 | 0.38 |
| ▸ | GPX4 | P36969 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.37 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | JAK2 | O60674 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1498662 | 0.98 | TSHR (0.50) | TSHRALDH1A1TP53NPC1RAB9A | |
| SCHEMBL1498625 | 0.95 | TSHR (0.45) | TSHRALDH1A1TP53CYP3A4CASP1 | |
| SCHEMBL16617376 | 0.93 | TSHR (0.45) | TSHRALDH1A1TP53NPC1RAB9A | |
| SCHEMBL16618123 | 0.92 | TSHR (0.47) | TSHRALDH1A1TP53NPC1RAB9A | |
| SCHEMBL16617890 | 0.92 | TSHR (0.47) | TSHRALDH1A1TP53NPC1RAB9A | |
| SCHEMBL16617357 | 0.91 | TSHR (0.42) | TSHRALDH1A1TP53CYP3A4CASP1 | |
| SCHEMBL16618153 | 0.88 | CYP3A4 (0.44) | TSHRALDH1A1TP53NPC1RAB9A | |
| SCHEMBL10139683 | 0.87 | CYP3A4 (0.42) | TSHRALDH1A1TP53CYP3A4CASP1 | |
| SCHEMBL10490585 | 0.83 | TSHR (0.49) | TSHRALDH1A1TP53NPC1RAB9A | |
| SCHEMBL10490559 | 0.83 | TSHR (0.49) | TSHRALDH1A1TP53NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2142496-B1 | LUBRICATING COMPOSITIONS CONTAINING ASHLESS CATALYTIC ANTIOXIDANT ADDITIVES | EXXONMOBIL RES & ENG CO (US) | 2013-04-17 | — | — | EP | disclosed |
| US-8080601-B2 | Lubricating compositions containing ashless catalytic antioxidant additives | EXXOMMOBIL RESEARCH AND ENGINEERING COMPANY (US) | 2011-12-20 | — | — | US | disclosed |
| EP-2142496-A1 | LUBRICATING COMPOSITIONS CONTAINING ASHLESS CATALYTIC ANTIOXIDANT ADDITIVES | ExxonMobil Research and Engineering Company (US) | 2010-01-13 | — | — | EP | disclosed |
| WO-2008121304-A1 | LUBRICATING COMPOSITIONS CONTAINING ASHLESS CATALYTIC ANTIOXIDANT ADDITIVES | EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) | 2008-10-09 | — | — | WO | disclosed |