Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | HTR7 | P34969 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | AR | P10275 | 1/20 | 0.36 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.36 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.36 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.36 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.36 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.36 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.36 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1498625 | 0.96 | TSHR (0.45) | TSHRHTR7ALDH1A1KDM4EPOLB | |
| SCHEMBL10139683 | 0.93 | CYP3A4 (0.42) | TSHRHTR7ALDH1A1MAPTCYP3A4 | |
| SCHEMBL3664908 | 0.91 | TSHR (0.47) | TSHRHTR7ALDH1A1KDM4EPOLB | |
| SCHEMBL16618153 | 0.90 | CYP3A4 (0.44) | TSHRHTR7ALDH1A1KDM4EPOLB | |
| SCHEMBL1498662 | 0.90 | TSHR (0.50) | TSHRALDH1A1KDM4EPOLBGAA | |
| SCHEMBL16617470 | 0.86 | TSHR (0.41) | TSHRHTR7ALDH1A1MAPTCYP3A4 | |
| SCHEMBL16617493 | 0.86 | CYP3A4 (0.47) | TSHRALDH1A1MAPTCYP3A4TP53 | |
| SCHEMBL16617376 | 0.85 | TSHR (0.45) | TSHRHTR7ALDH1A1KDM4ECYP3A4 | |
| SCHEMBL16616912 | 0.85 | ALDH1A1 (0.37) | TSHRHTR7ALDH1A1KDM4ECYP3A4 | |
| SCHEMBL15263454 | 0.84 | KDM4E (0.36) | TSHRHTR7ALDH1A1KDM4ETP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2828339-B1 | CARBOXYLATE DYES | MILLIKEN & CO (US) | 2018-10-31 | — | — | EP | disclosed |
| US-9187717-B2 | Carboxylate dyes | MILLIKEN & COMPANY (US) | 2015-11-17 | — | — | US | disclosed |
| US-20150099869-A1 | Carboxylate Dyes | MILLIKEN & COMPANY | 2015-04-09 | — | — | US | disclosed |