SCHEMBL10139683

SCHEMBL10139683

CCCN(CCC)c1cccc(N)c1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 5/20 0.42
RECQL P46063 2/20 0.42
CASP1 P29466 1/20 0.42
ALDH1A1 P00352 5/20 0.41
TP53 P04637 1/20 0.41
MAPT P10636 1/20 0.40
TSHR P16473 3/20 0.40
HTR7 P34969 1/20 0.38
MAPK1 P28482 2/20 0.38
TDP1 Q9NUW8 2/20 0.38
PSMD14 O00487 1/20 0.38
GFER P55789 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
SYK P43405 1/20 0.37
S1PR1 P21453 1/20 0.36
S100B P04271 1/20 0.36
CA12 O43570 1/20 0.35
CA1 P00915 1/20 0.35
CA2 P00918 1/20 0.35
CA7 P43166 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16617357 0.93 TSHR (0.42) CYP3A4RECQLCASP1ALDH1A1TP53
SCHEMBL16617493 0.92 CYP3A4 (0.47) CYP3A4RECQLCASP1ALDH1A1TP53
SCHEMBL1498625 0.89 TSHR (0.45) CYP3A4RECQLCASP1ALDH1A1TP53
SCHEMBL16618104 0.88 TSHR (0.40) CYP3A4RECQLCASP1ALDH1A1TP53
SCHEMBL16617287 0.87 MAOB (0.50) MAOAMAOB
SCHEMBL16618016 0.87 ALOX15 (0.42) CYP3A4RECQLCASP1ALDH1A1TP53
SCHEMBL3664908 0.87 TSHR (0.47) CYP3A4RECQLCASP1ALDH1A1TP53
SCHEMBL16617470 0.86 TSHR (0.41) CYP3A4ALDH1A1TP53MAPTTSHR
SCHEMBL1498662 0.85 TSHR (0.50) CYP3A4RECQLCASP1ALDH1A1TP53
SCHEMBL16616912 0.84 ALDH1A1 (0.37) CYP3A4ALDH1A1TP53TSHRHTR7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114072000-A Molecules having certain pesticidal effects and intermediates, compositions and methods related thereto 科迪华农业科技有限责任公司 2022-02-18 CN disclosed
EP-2828339-B1 CARBOXYLATE DYES MILLIKEN & CO (US) 2018-10-31 EP disclosed
US-9187717-B2 Carboxylate dyes MILLIKEN & COMPANY (US) 2015-11-17 US disclosed
US-20150099869-A1 Carboxylate Dyes MILLIKEN & COMPANY 2015-04-09 US disclosed
CN-104350106-A Laundry care compositions containing dyes PROCTER & GAMBLE 2015-02-11 CN disclosed
EP-2828340-A1 LAUNDRY CARE COMPOSITIONS CONTAINING DYES The Procter & Gamble Company (US) 2015-01-28 EP disclosed
CN-104220535-A Carboxylate dyes MILLIKEN & CO 2014-12-17 CN disclosed
WO-2013142486-A1 LAUNDRY CARE COMPOSITIONS CONTAINING DYES THE PROCTER & GAMBLE COMPANY (US) 2013-09-26 WO disclosed
WO-2012059932-A1 2, 4 -DIAMINOPYRIMIDINE DERIVATIVES AS PROTEIN KINASE INHIBITORS AURIGENE DISCOVERY TECHNOLOGIES LIMITED (IN) 2012-05-10 WO disclosed