Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
| ▸ | DPP4 | P27487 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | GMNN | O75496 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | MLNR | O43193 | 1/20 | 0.34 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.34 |
| ▸ | EGFR | P00533 | 1/20 | 0.34 |
| ▸ | FYN | P06241 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10885009 | 0.74 | SHBG (0.38) | EPHX1TP53LMNAKDM4EGMNN | |
| SCHEMBL2781157 | 0.71 | EPHX1 (0.48) | EPHX1DPP4TP53LMNAKDM4E | |
| SCHEMBL18849500 | 0.71 | EPHX1 (0.48) | EPHX1DPP4TP53LMNAKDM4E | |
| SCHEMBL23022847 | 0.70 | EPHX1 (0.37) | EPHX1DPP4TP53SIGMAR1 | |
| SCHEMBL19982043 | 0.70 | EPHX1 (0.37) | EPHX1DPP4TP53SIGMAR1 | |
| SCHEMBL4238451 | 0.69 | ANPEP (0.36) | EPHX1DPP4TP53LMNAKDM4E | |
| SCHEMBL8070691 | 0.69 | EPHX1 (0.59) | EPHX1DPP4TP53LMNAKDM4E | |
| SCHEMBL21656667 | 0.69 | EPHX1 (0.59) | EPHX1DPP4TP53LMNAKDM4E | |
| SCHEMBL5700121 | 0.69 | EPHX1 (0.59) | EPHX1DPP4TP53LMNAKDM4E | |
| Cyclohexane SCHEMBL2492289 | 0.69 | EPHX1 (0.59) | EPHX1DPP4TP53LMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104946267-B | Aligning agent for liquid crystal, liquid crystal orientation film and its preparation method, liquid crystal display element, phase difference film and its preparation method, polymer and compound | JSR株式会社 | 2019-06-11 | — | — | CN | disclosed |
| EP-2139337-A1 | INHIBITORS OF FIBROBLAST ACTIVATION PROTEIN, AND METHODS OF USE THEREOF | Trustees Of Tufts College (US) | 2010-01-06 | — | — | EP | disclosed |
| WO-2008116054-A1 | INHIBITORS OF FIBROBLAST ACTIVATION PROTEIN, AND METHODS OF USE THEREOF | TRUSTEES OF TUFTS COLLEGE (US) | 2008-09-25 | — | — | WO | disclosed |
| EP-1948243-A2 | POLYCATION-POLYANION COMPLEXES, COMPOSITIONS AND METHODS OF USE THEREOF | Aeris Therapeutics, Inc. (US) | 2008-07-30 | — | — | EP | disclosed |
| WO-2007055950-A2 | POLYCATION-POLYANION COMPLEXES, COMPOSITIONS AND METHODS OF USE THEREOF | AERIS THERAPEUTICS, INC. (US) | 2007-05-18 | — | — | WO | disclosed |