Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 12/20 | 0.48 |
| ▸ | HPGD | P15428 | 10/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.48 |
| ▸ | IGLV6-57 | P01721 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.43 |
| ▸ | MAOB | P27338 | 2/20 | 0.43 |
| ▸ | GLA | P06280 | 2/20 | 0.43 |
| ▸ | CASP1 | P29466 | 2/20 | 0.43 |
| ▸ | CASP7 | P55210 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.43 |
| ▸ | UGT1A1 | P22309 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Propane SCHEMBL27925750 | 0.80 | MAOA (0.68) | MAOAALDH1A1HPGDKDM4EIGLV6-57 | |
| SCHEMBL29474940 | 0.78 | MAOA (0.74) | MAOAALDH1A1HPGDKDM4EIGLV6-57 | |
| SCHEMBL66891 | 0.78 | MAOA (0.74) | MAOAALDH1A1HPGDKDM4EIGLV6-57 | |
| Diethylamine SCHEMBL1306508 | 0.78 | MAOA (0.60) | MAOAALDH1A1HPGDKDM4EIGLV6-57 | |
| Alcohol SCHEMBL11228664 | 0.77 | MAOA (0.64) | MAOAALDH1A1HPGDKDM4EIGLV6-57 | |
| Ethylamine SCHEMBL8340171 | 0.77 | MAOA (0.64) | MAOAALDH1A1HPGDKDM4EIGLV6-57 | |
| Phosphoric Acid SCHEMBL27718718 | 0.77 | MAOA (0.64) | MAOAALDH1A1HPGDKDM4ELMNA | |
| SCHEMBL27924128 | 0.77 | MAOA (0.72) | MAOAALDH1A1HPGDKDM4EIGLV6-57 | |
| Water SCHEMBL28315263 | 0.77 | MAOA (0.72) | MAOAALDH1A1HPGDKDM4EIGLV6-57 | |
| Hydrochloric Acid SCHEMBL27839067 | 0.77 | MAOA (0.72) | MAOAALDH1A1HPGDKDM4EIGLV6-57 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2152368-A1 | SUBSTITUTED PHOSPHONATES AND THEIR USE IN DECREASING AMYLOID AGGREGATES | Queen Mary and Westfield College (GB) | 2010-02-17 | — | — | EP | disclosed |
| WO-2008135743-A1 | SUBSTITUTED PHOSPHONATES AND THEIR USE IN DECREASING AMYLOID AGGREGATES | QUEEN MARY AND WESTFIELD COLLEGE (GB) | 2008-11-13 | — | — | WO | disclosed |