Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYR | P14679 | 3/20 | 0.38 |
| ▸ | CTRC | Q99895 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.33 |
| ▸ | PDE4A | P27815 | 3/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.33 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.33 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.33 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.33 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20869442 | 0.80 | TYR (0.39) | TYRCTRCCYP3A4CYP2D6CYP2C9 | |
| SCHEMBL12339026 | 0.79 | TYR (0.40) | TYRCTRCCYP3A4CYP2D6CYP2C9 | |
| SCHEMBL30613910 | 0.79 | TYR (0.40) | TYRCTRCCYP3A4CYP2D6CYP2C9 | |
| SCHEMBL4457865 | 0.78 | LTB4R (0.45) | TYRCTRCLIPGPDE4APDE4B | |
| SCHEMBL9243142 | 0.78 | TYR (0.38) | TYRCTRCLIPGPDE4APDE4B | |
| SCHEMBL4170722 | 0.77 | TYR (0.37) | TYRCTRCCYP3A4CYP2D6CYP2C9 | |
| SCHEMBL2965801 | 0.77 | TYR (0.41) | TYRCTRCCYP3A4CYP2D6CYP2C9 | |
| SCHEMBL2971165 | 0.77 | TYR (0.37) | TYRCTRCCYP3A4CYP2D6CYP2C9 | |
| SCHEMBL9769203 | 0.77 | TYR (0.37) | TYRCTRCCYP3A4CYP2D6CYP2C9 | |
| SCHEMBL28681524 | 0.77 | TLR8 (0.39) | TYRCTRCCYP2D6CYP2C9LIPG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2593449-A1 | PROCESS FOR THE SYNTHESIS OF BENZOTHIADIAZOLE COMPOUNDS | ENI S.p.A. (IT) | 2013-05-22 | — | — | EP | disclosed |
| WO-2012007834-A1 | PROCESS FOR THE SYNTHESIS OF BENZOTHIADIAZOLE COMPOUNDS | ENI S.P.A. (IT) | 2012-01-19 | — | — | WO | disclosed |