Remifentanil

Remifentanil

SCHEMBL36652

CCC(=O)N(c1ccccc1)C1(C(=O)OC)CCN(CCC(=O)OC)CC1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

OPRM1

The experimentally established mechanism targets of Remifentanil. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
OPRM1 known ✓ P35372 14/20 0.77
CACNA1C Q13936 1/20 1.00
OPRD1 P41143 5/20 0.77
OPRK1 P41145 2/20 0.77

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Remifentanil SCHEMBL17874058 1.00 CACNA1C (1.00) CACNA1COPRM1OPRD1OPRK1
Remifentanil SCHEMBL3711219 0.99 CACNA1C (0.98) CACNA1COPRM1OPRD1OPRK1
Remifentanil SCHEMBL29846323 0.99 CACNA1C (0.98) CACNA1COPRM1OPRD1OPRK1
Remifentanil SCHEMBL41242 0.99 CACNA1C (0.98) CACNA1COPRM1OPRD1OPRK1
Remifentanil SCHEMBL3423820 0.99 CACNA1C (0.98) CACNA1COPRM1OPRD1OPRK1
Remifentanil SCHEMBL27828413 0.98 CACNA1C (0.96) CACNA1COPRM1OPRD1OPRK1
Remifentanil SCHEMBL1649640 0.98 CACNA1C (0.96) CACNA1COPRM1OPRD1OPRK1
Remifentanil SCHEMBL8446617 0.95 CACNA1C (0.90) CACNA1COPRM1OPRD1OPRK1
Carfentanil SCHEMBL16444962 0.94 OPRM1 (0.89) CACNA1COPRM1OPRD1OPRK1
Remifentanil SCHEMBL4384648 0.94 CACNA1C (0.89) CACNA1COPRM1OPRD1OPRK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 12890 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122087518-A Method for classifying anesthetic drugs by using neural network 2026-05-26 CN claimed
US-12635940-B2 Closed-loop drug infusion system with synergic control UNIVERSIDAD POLITÉCNICA DE MADRID FUNDACION PARA LA INVESTIGACIÓN E INNOVACIÓN BIOMÉDICA (ES) 2026-05-26 US claimed
EP-4255391-B1 LUMINOL FOR USE IN THE TREATMENT OF SEQUELAE OF A SARS-COV-2 INFECTION METRIOPHARM AG (CH) 2026-05-06 EP claimed
EP-4719552-A1 INDUCTION OF GENERAL ANESTHESIA IN ADULTS UNDERGOING ELECTIVE SURGERY Xizang Haisco Pharmaceutical Co., Ltd. (CN) 2026-04-08 EP claimed
US-20260069777-A1 Systems and methods for controlled delivery of analgesic and hypnotic agents NEUROWAVE SYSTEMS INC. (CA) 2026-03-12 US claimed
CN-121577732-A Method for rapidly detecting remifentanil blood concentration 中国科学院大连化学物理研究所 2026-02-27 CN claimed
US-20260027128-A1 ORALLY INHALED AND NASAL BENZODIAZEPINES PAION UK LTD (GB) 2026-01-29 US claimed
US-20260027337-A1 TRANSDERMAL DRUG DELIVERY DEVICES AND METHODS MORNINGSIDE VENTURE INVESTMENTS LTD (MC) 2026-01-29 US claimed
US-20260021038-A1 Compositions and Methods for the Treatment of Opioid Overdose INDIVIOR INC (US) 2026-01-22 US claimed
EP-4680244-A1 SEROTONIN 5HT2A RECEPTOR ANTAGONIST FOR USE IN TREATING SIDE EFFECTS RESULTING FORM MU OPIOID RECEPTOR AGONIST OVERDOSE Norwegian University Of Life Sciences (NO) 2026-01-21 EP claimed
WO-1998035888-A1 METERING VALVE FOR AEROSOLS GLAXO GROUP LIMITED (GB) 1998-08-20 WO claimed
EP-0759744-A4 NARCOTIC CONTAINING AEROSOL FORMULATION ARADIGM CORP (US) 1997-10-29 EP claimed
US-5635204-A Method for transdermal induction of anesthesia, analgesia or sedation MONTEFIORE MEDICAL CENTER (US) 1997-06-03 US claimed
EP-0759744-A1 NARCOTIC CONTAINING AEROSOL FORMULATION ARADIGM CORPORATION (US) 1997-03-05 EP claimed
EP-0726864-A1 METERED AEROSOL DISPENSING APPARATUS AND METHOD OF USE THEREOF GLAXO WELLCOME INC. (US) 1996-08-21 EP claimed
EP-0383579-B1 N-Phenyl-N-(4-piperidinyl)amides useful as analgesics GLAXO WELLCOME INC (US) 1996-07-17 EP claimed
WO-1995031182-A1 NARCOTIC CONTAINING AEROSOL FORMULATION ARADIGM CORPORATION (US) 1995-11-23 WO claimed
US-5421492-A Metered aerosol dispensing apparatus and method of use thereof GLAXO INC. (US) 1995-06-06 US claimed
WO-1995012533-A1 METERED AEROSOL DISPENSING APPARATUS AND METHOD OF USE THEREOF GLAXO WELLCOME INC. (US) 1995-05-11 WO claimed
EP-0383579-A1 N-Phenyl-N-(4-piperidinyl)amides useful as analgesics GLAXO WELLCOME INC. (US) 1990-08-22 EP claimed