Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 19/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL910254 | 0.92 | KCNH2 (0.55) | KCNH2 | |
| SCHEMBL3839224 | 0.91 | KCNH2 (0.72) | KCNH2 | |
| SCHEMBL910255 | 0.89 | KCNH2 (0.52) | KCNH2 | |
| SCHEMBL4140282 | 0.85 | KCNH2 (0.63) | KCNH2 | |
| SCHEMBL3859386 | 0.83 | KCNH2 (0.72) | KCNH2 | |
| SCHEMBL4779465 | 0.82 | KCNH2 (0.65) | KCNH2 | |
| SCHEMBL4779477 | 0.82 | KCNH2 (0.57) | KCNH2 | |
| SCHEMBL4296810 | 0.81 | KCNH2 (0.57) | KCNH2 | |
| SCHEMBL909967 | 0.81 | KCNH2 (0.45) | KCNH2 | |
| SCHEMBL910385 | 0.81 | KCNH2 (0.45) | KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2238138-A1 | TRICYCLIC NITROGEN COMPOUNDS AND THEIR USE AS ANTIBACTERIAL AGENTS | Glaxo Group Limited (GB) | 2010-10-13 | — | — | EP | disclosed |
| WO-2009087153-A1 | TRICYCLIC NITROGEN COMPOUNDS AND THEIR USE AS ANTIBACTERIAL AGENTS | GLAXO GROUP LIMITED (GB) | 2009-07-16 | — | — | WO | disclosed |