Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 18/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4779477 | 0.92 | KCNH2 (0.57) | KCNH2 | |
| SCHEMBL3665289 | 0.89 | KCNH2 (0.60) | KCNH2 | |
| SCHEMBL4778509 | 0.87 | KCNH2 (0.51) | KCNH2 | |
| SCHEMBL4778712 | 0.85 | KCNH2 (0.57) | KCNH2 | |
| SCHEMBL910254 | 0.83 | KCNH2 (0.55) | KCNH2 | |
| SCHEMBL3839224 | 0.82 | KCNH2 (0.72) | KCNH2 | |
| SCHEMBL6080762 | 0.81 | KCNH2 (0.60) | KCNH2 | |
| SCHEMBL4775988 | 0.79 | KCNH2 (0.51) | KCNH2 | |
| SCHEMBL4778333 | 0.79 | KCNH2 (0.43) | KCNH2 | |
| SCHEMBL4140282 | 0.77 | KCNH2 (0.63) | KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110009394-A1 | TRICYCLIC NITROGEN COMPOUNDS AND THEIR USE AS ANTIBACTERIAL AGENTS | GLAXO GROUP LIMITED (GB) | 2011-01-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110009394-A1 | TRICYCLIC NITROGEN COMPOUNDS AND THEIR USE AS ANTIBACTERIAL AGENTS | NRDC, NCL, NPM1 | KCNH2 3726/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.