Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 18/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4778509 | 0.95 | KCNH2 (0.51) | KCNH2 | |
| SCHEMBL4778712 | 0.93 | KCNH2 (0.57) | KCNH2 | |
| SCHEMBL910255 | 0.92 | KCNH2 (0.52) | KCNH2 | |
| SCHEMBL3839224 | 0.88 | KCNH2 (0.72) | KCNH2 | |
| SCHEMBL4775988 | 0.87 | KCNH2 (0.51) | KCNH2 | |
| SCHEMBL4778333 | 0.86 | KCNH2 (0.43) | KCNH2 | |
| SCHEMBL4775755 | 0.84 | KCNH2 (0.41) | KCNH2 | |
| SCHEMBL3665289 | 0.82 | KCNH2 (0.60) | KCNH2 | |
| SCHEMBL4140282 | 0.82 | KCNH2 (0.63) | KCNH2 | |
| SCHEMBL4779465 | 0.82 | KCNH2 (0.65) | KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1992628-A1 | Derivatives and analogs of N-ethylquinolones and N-ethylazaquinolones | GLAXO GROUP LIMITED (GB) | 2008-11-19 | — | — | EP | disclosed |