Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F11 | P03951 | 18/20 | 0.47 |
| ▸ | KLKB1 | P03952 | 7/20 | 0.47 |
| ▸ | F9 | P00740 | 1/20 | 0.47 |
| ▸ | KLK1 | P06870 | 8/20 | 0.46 |
| ▸ | MASP2 | O00187 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2994837 | 0.87 | F11 (0.61) | F11KLKB1F9KLK1 | |
| SCHEMBL2994833 | 0.87 | F11 (0.61) | F11KLKB1F9KLK1 | |
| SCHEMBL28974397 | 0.76 | F9 (0.55) | F11KLKB1F9KLK1 | |
| SCHEMBL3664533 | 0.75 | F11 (0.66) | F11KLKB1F9 | |
| SCHEMBL3668964 | 0.75 | F9 (0.52) | F11KLKB1F9KLK1 | |
| SCHEMBL3666528 | 0.74 | F11 (0.52) | F11KLKB1F9KLK1 | |
| SCHEMBL3663969 | 0.74 | F11 (0.58) | F11KLKB1 | |
| SCHEMBL13267329 | 0.74 | F11 (0.64) | F11KLKB1F9KLK1 | |
| SCHEMBL3664217 | 0.72 | F11 (0.76) | F11KLKB1F9 | |
| SCHEMBL3671633 | 0.72 | F11 (0.62) | F11KLKB1F9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2152664-A1 | DIPEPTIDE ANALOGS AS COAGULATION FACTOR INHIBITORS | Brystol-Myers Squibb Company (US) | 2010-02-17 | — | — | EP | disclosed |
| WO-2008157162-A1 | DIPEPTIDE ANALOGS AS COAGULATION FACTOR INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2008-12-24 | — | — | WO | disclosed |