Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F11 | P03951 | 18/20 | 0.52 |
| ▸ | KLK1 | P06870 | 8/20 | 0.51 |
| ▸ | F9 | P00740 | 2/20 | 0.51 |
| ▸ | KLKB1 | P03952 | 8/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3004445 | 0.87 | F11 (0.59) | F11KLK1F9KLKB1 | |
| SCHEMBL3004443 | 0.87 | F11 (0.59) | F11KLK1F9KLKB1 | |
| SCHEMBL3668964 | 0.85 | F9 (0.52) | F11KLK1F9KLKB1 | |
| SCHEMBL28974397 | 0.82 | F9 (0.55) | F11KLK1F9KLKB1 | |
| SCHEMBL3664533 | 0.80 | F11 (0.66) | F11F9KLKB1 | |
| SCHEMBL3004448 | 0.75 | F11 (0.49) | F11KLK1F9KLKB1 | |
| SCHEMBL3664441 | 0.74 | F11 (0.62) | F11KLKB1 | |
| SCHEMBL3665491 | 0.74 | F11 (0.47) | F11KLK1F9KLKB1 | |
| SCHEMBL3664443 | 0.74 | F11 (0.62) | F11KLKB1 | |
| SCHEMBL3665318 | 0.74 | F11 (0.58) | F11KLKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2152664-A1 | DIPEPTIDE ANALOGS AS COAGULATION FACTOR INHIBITORS | Brystol-Myers Squibb Company (US) | 2010-02-17 | — | — | EP | disclosed |
| WO-2008157162-A1 | DIPEPTIDE ANALOGS AS COAGULATION FACTOR INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2008-12-24 | — | — | WO | disclosed |