Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APEX1 | P27695 | 2/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.51 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | GFER | P55789 | 1/20 | 0.47 |
| ▸ | HTR1A | P08908 | 1/20 | 0.47 |
| ▸ | HTR2A | P28223 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL366415 | 1.00 | APEX1 (0.60) | APEX1CYP1A2CYP2D6CYP3A4CYP2C19 | |
| SCHEMBL367521 | 1.00 | APEX1 (0.60) | APEX1CYP1A2CYP2D6CYP3A4CYP2C19 | |
| SCHEMBL367761 | 1.00 | APEX1 (0.60) | APEX1CYP1A2CYP2D6CYP3A4CYP2C19 | |
| SCHEMBL367336 | 1.00 | APEX1 (0.60) | APEX1CYP1A2CYP2D6CYP3A4CYP2C19 | |
| SCHEMBL13920083 | 1.00 | APEX1 (0.60) | APEX1CYP1A2CYP2D6CYP3A4CYP2C19 | |
| SCHEMBL9811262 | 0.83 | MAPT (0.52) | APEX1CYP1A2CYP2D6CYP3A4CYP2C19 | |
| SCHEMBL9811199 | 0.82 | MAPT (0.51) | APEX1CYP1A2CYP2D6CYP3A4CYP2C19 | |
| SCHEMBL366062 | 0.82 | APEX1 (0.57) | APEX1CYP1A2CYP2D6CYP3A4CYP2C19 | |
| SCHEMBL10037465 | 0.81 | APEX1 (0.50) | APEX1CYP1A2CYP2D6CYP3A4CYP2C19 | |
| SCHEMBL14028805 | 0.81 | APEX1 (0.53) | APEX1MAPK1L3MBTL1MAPTPTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4679518-B2 | — | — | 2011-04-27 | — | — | JP | claimed |
| EP-1654342-B1 | REACTION PRODUCTS OF MERCAPTOBENZOTHIAZOLES, MERCAPTOTHIAZOLINES, AND MERCAPTOBENZIMIDAZOLES WITH EPOXIDES AS LUBRICANT ADDITIVES | CHEMTURA CORP (US) | 2011-01-19 | — | — | EP | claimed |
| US-7442673-B2 | Reaction products of mercaptobenzothiazoles, mercaptothiazolines, and mercaptobenzimidazoles with epoxides as lubricant additives | CROMPTON CORPORATION (US) | 2008-10-28 | — | — | US | claimed |
| JP-2007502870-A | — | — | 2007-02-15 | — | — | JP | claimed |
| EP-1654342-A1 | REACTIONS PRODUCTS OF MERCAPTOBENZOTHIAZOLES, MERCAPTOTHIAZOLINES, AND MERCAPTOBENZIMIDAZOLES WITH EPOXIDES AS LUBRICANT ADDITIVES | CHEMTURA CORPORATION (US) | 2006-05-10 | — | — | EP | claimed |
| WO-2005019396-A1 | REACTIONS PRODUCTS OF MERCAPTOBENZOTHIAZOLES, MERCAPTOTHIAZOLINES, AND MERCAPTOBENZIMIDAZOLES WITH EPOXIDES AS LUBRICANT ADDITIVES | CHEMTURA CORPORATION (US) | 2005-03-03 | — | — | WO | claimed |
| US-20050037931-A1 | Reaction products of mercaptobenzothiazoles, mercaptothiazolines, and mercaptobenzimidazoles with epoxides as lubricant additives | CHEMTURA CORPORATION | 2005-02-17 | — | — | US | claimed |
| US-8097731-B2 | Reaction products of mercaptobenzothiazoles, mercaptothiazolines, and mercaptobenzimidalzoles with epoxides as lubricant additives | CROMPTON CORPORATION (US) | 2012-01-17 | — | — | US | disclosed |
| EP-1654342-B1 | REACTION PRODUCTS OF MERCAPTOBENZOTHIAZOLES, MERCAPTOTHIAZOLINES, AND MERCAPTOBENZIMIDAZOLES WITH EPOXIDES AS LUBRICANT ADDITIVES | CHEMTURA CORP (US) | 2011-01-19 | — | — | EP | disclosed |
| US-20090076279-A1 | REACTION PRODUCTS OF MERCAPTOBENZOTHIAZOLES, MERCAPTOTHIAZOLINES, AND MERCAPTOBENZIMIDAZOLES WITH EPOXIDES AS LUBRICANT ADDITIVES | CHEMTURA CORPORATION | 2009-03-19 | — | — | US | disclosed |
| US-7442673-B2 | Reaction products of mercaptobenzothiazoles, mercaptothiazolines, and mercaptobenzimidazoles with epoxides as lubricant additives | CROMPTON CORPORATION (US) | 2008-10-28 | — | — | US | disclosed |
| EP-1654342-A1 | REACTIONS PRODUCTS OF MERCAPTOBENZOTHIAZOLES, MERCAPTOTHIAZOLINES, AND MERCAPTOBENZIMIDAZOLES WITH EPOXIDES AS LUBRICANT ADDITIVES | CHEMTURA CORPORATION (US) | 2006-05-10 | — | — | EP | disclosed |
| WO-2005019396-A1 | REACTIONS PRODUCTS OF MERCAPTOBENZOTHIAZOLES, MERCAPTOTHIAZOLINES, AND MERCAPTOBENZIMIDAZOLES WITH EPOXIDES AS LUBRICANT ADDITIVES | CHEMTURA CORPORATION (US) | 2005-03-03 | — | — | WO | disclosed |
| US-20050037931-A1 | Reaction products of mercaptobenzothiazoles, mercaptothiazolines, and mercaptobenzimidazoles with epoxides as lubricant additives | CHEMTURA CORPORATION | 2005-02-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090076279-A1 | REACTION PRODUCTS OF MERCAPTOBENZOTHIAZOLES, MERCAPTOTHIAZOLINES, AND MERCAPTOBENZIMIDAZOLES WITH EPOXIDES AS LUBRICANT ADDITIVES | EPX, CYP2E1, AOX1 | APEX1 832/4885CYP1A2 74/4885CYP2D6 113/4885 |
| US-20050037931-A1 | Reaction products of mercaptobenzothiazoles, mercaptothiazolines, and mercaptobenzimidazoles with epoxides as lubricant additives | CBR1, CBR3, OR10J3 | APEX1 1441/4885CYP1A2 273/4885CYP2D6 219/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.