Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | SAE1 | Q9UBE0 | 2/20 | 0.44 |
| ▸ | UBA2 | Q9UBT2 | 2/20 | 0.44 |
| ▸ | APAF1 | O14727 | 1/20 | 0.44 |
| ▸ | G6PD | P11413 | 1/20 | 0.44 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.44 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.44 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.44 |
| ▸ | CASP3 | P42574 | 1/20 | 0.43 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL365015 | 0.88 | ALDH1A1 (0.58) | KDM4EALDH1A1EPHX1KMT2AMEN1 | |
| SCHEMBL366561 | 0.85 | KMT2A (0.45) | KDM4EALDH1A1EPHX1KMT2AMEN1 | |
| SCHEMBL365667 | 0.83 | EPHX1 (0.56) | KDM4EALDH1A1EPHX1KMT2AMEN1 | |
| SCHEMBL365100 | 0.83 | EPHX1 (0.52) | KDM4EALDH1A1EPHX1KMT2AMEN1 | |
| SCHEMBL366405 | 0.80 | KMT2A (0.50) | KDM4EALDH1A1KMT2AMEN1MAPT | |
| SCHEMBL364757 | 0.79 | ALDH1A1 (0.61) | KDM4EALDH1A1KMT2AMEN1MAPT | |
| SCHEMBL10274108 | 0.79 | ALDH1A1 (0.57) | KDM4EALDH1A1KMT2AMEN1MAPT | |
| SCHEMBL365561 | 0.77 | ALDH1A1 (0.47) | KDM4EALDH1A1KMT2AMEN1MAPT | |
| SCHEMBL365116 | 0.76 | ALDH1A1 (0.52) | KDM4EALDH1A1KMT2AMEN1MAPT | |
| SCHEMBL365133 | 0.76 | KMT2A (0.57) | KDM4EALDH1A1EPHX1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012007007-A1 | INHIBITORS OF HDME | EPITHERAPEUTICS APS (DK) | 2012-01-19 | — | — | WO | claimed |
| WO-2012007008-A1 | INHIBITORS OF HDME | EPITHERAPEUTICS APS (DK) | 2012-01-19 | — | — | WO | disclosed |
| WO-2012007008-A1 | INHIBITORS OF HDME | EPITHERAPEUTICS APS (DK) | 2012-01-19 | — | — | WO | disclosed |
| WO-2012007007-A1 | INHIBITORS OF HDME | EPITHERAPEUTICS APS (DK) | 2012-01-19 | — | — | WO | disclosed |
| WO-2012007007-A1 | INHIBITORS OF HDME | EPITHERAPEUTICS APS (DK) | 2012-01-19 | — | — | WO | disclosed |