Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | APOBEC3A | P31941 | 3/20 | 0.42 |
| ▸ | APOBEC3G | Q9HC16 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | CHRNB2 | P17787 | 3/20 | 0.40 |
| ▸ | CHRNB4 | P30926 | 3/20 | 0.40 |
| ▸ | CHRNA3 | P32297 | 3/20 | 0.40 |
| ▸ | CHRNA7 | P36544 | 3/20 | 0.40 |
| ▸ | CHRNA4 | P43681 | 3/20 | 0.40 |
| ▸ | CHRNA10 | Q9GZZ6 | 3/20 | 0.40 |
| ▸ | CHRNA9 | Q9UGM1 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | BBOX1 | O75936 | 2/20 | 0.38 |
| ▸ | CDC25A | P30304 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 3/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | CTDSP1 | Q9GZU7 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL372822 | 0.73 | KDM4E (0.95) | KDM4EAPOBEC3AAPOBEC3GLMNACHRNB2 | |
| SCHEMBL718386 | 0.73 | KDM4E (0.95) | KDM4EAPOBEC3AAPOBEC3GLMNACHRNB2 | |
| SCHEMBL5944464 | 0.72 | KDM4E (0.57) | KDM4EAPOBEC3AAPOBEC3GLMNACHRNB2 | |
| SCHEMBL16674108 | 0.72 | KDM4E (0.62) | KDM4EAPOBEC3AAPOBEC3GLMNACHRNB2 | |
| SCHEMBL23050168 | 0.72 | KDM4E (0.47) | KDM4EAPOBEC3AAPOBEC3GLMNACHRNB2 | |
| SCHEMBL19812383 | 0.72 | KDM4E (0.57) | KDM4EAPOBEC3AAPOBEC3GLMNACHRNB2 | |
| Water SCHEMBL15375367 | 0.71 | KDM4E (0.91) | KDM4EAPOBEC3AAPOBEC3GLMNACHRNB2 | |
| Iodide SCHEMBL14877089 | 0.71 | KDM4E (1.00) | KDM4EAPOBEC3AAPOBEC3GLMNACHRNB2 | |
| Iodide SCHEMBL720052 | 0.71 | KDM4E (1.00) | KDM4EAPOBEC3AAPOBEC3GLMNACHRNB2 | |
| SCHEMBL23484981 | 0.71 | KDM4E (0.61) | KDM4EAPOBEC3AAPOBEC3GLMNACHRNB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8097752-B2 | Antiprotozoal ring-substituted phospholipids | MAKSCIENTIFIC, LLC (US) | 2012-01-17 | — | — | US | disclosed |
| US-20060105998-A1 | Antiprotozoal ring-substiuted phospholipids | MAK SCIENTIFIC CORPORATION (US) | 2006-05-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060105998-A1 | Antiprotozoal ring-substiuted phospholipids | PHOSPHO1, PLTP, PLA2G2C | KDM4E 3491/4885APOBEC3A 3220/4885APOBEC3G 3357/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.