Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FSHR | P23945 | 1/20 | 0.38 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.37 |
| ▸ | PTGDR2 | Q9Y5Y4 | 3/20 | 0.36 |
| ▸ | PPARG | P37231 | 2/20 | 0.36 |
| ▸ | PPARA | Q07869 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.35 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.35 |
| ▸ | FAAH | O00519 | 1/20 | 0.35 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.35 |
| ▸ | PTGES | O14684 | 3/20 | 0.35 |
| ▸ | CETP | P11597 | 2/20 | 0.34 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.34 |
| ▸ | PTGDR | Q13258 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | PTGIR | P43119 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3665828 | 0.91 | FSHR (0.38) | FSHRS1PR1PTGDR2PPARGPPARA | |
| SCHEMBL3666381 | 0.88 | S1PR1 (0.43) | FSHRS1PR1PTGDR2CYP2D6CACNA1B | |
| SCHEMBL1948049 | 0.87 | PTGDR2 (0.53) | PTGDR2PPARGPPARALTB4R2 | |
| SCHEMBL3667568 | 0.85 | MGLL (0.42) | S1PR1PTGDR2CACNA1BFAAHLTB4R2 | |
| SCHEMBL3667985 | 0.84 | HDAC6 (0.41) | PPARGPPARACYP2D6PTGESCETP | |
| SCHEMBL3666210 | 0.83 | FSHR (0.40) | FSHRS1PR1PTGDR2PPARGPPARA | |
| SCHEMBL3731304 | 0.82 | CTSA (0.39) | S1PR1PTGDR2PPARGPPARACYP2D6 | |
| SCHEMBL3670881 | 0.81 | PTGDR2 (0.44) | S1PR1PTGDR2LTB4R2 | |
| SCHEMBL3666383 | 0.79 | S1PR1 (0.43) | FSHRS1PR1PTGDR2CYP2D6CACNA1B | |
| SCHEMBL1946723 | 0.79 | PTGDR2 (0.51) | PTGDR2PPARGPPARALTB4R2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2240434-A1 | 2-PHENYL PHENOXYACETIC ACIDS USEFUL FOR TREATING INFLAMMATORY DISORDERS | Ligand Pharmaceuticals Inc. (US) | 2010-10-20 | — | — | EP | claimed |
| WO-2009089192-A1 | 2-PHENYL PHENOXYACETIC ACIDS USEFUL FOR TREATING INFLAMMATORY DISORDERS | LIGAND PHARMACEUTICALS INC. (US) | 2009-07-16 | — | — | WO | claimed |
| EP-2240434-A1 | 2-PHENYL PHENOXYACETIC ACIDS USEFUL FOR TREATING INFLAMMATORY DISORDERS | Ligand Pharmaceuticals Inc. (US) | 2010-10-20 | — | — | EP | disclosed |
| WO-2009089192-A1 | 2-PHENYL PHENOXYACETIC ACIDS USEFUL FOR TREATING INFLAMMATORY DISORDERS | LIGAND PHARMACEUTICALS INC. (US) | 2009-07-16 | — | — | WO | disclosed |