SCHEMBL1948049

SCHEMBL1948049

CCCCOC(=O)N(CC(=O)NC)Cc1cccc(-c2cc(C(F)(F)F)ccc2OCC(=O)O)c1

nearest known ligand 0.53

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
PTGDR2 Q9Y5Y4 14/20 0.53
PPARD Q03181 4/20 0.41
LTB4R2 Q9NPC1 1/20 0.41
FFAR1 O14842 2/20 0.40
PPARG P37231 1/20 0.40
PPARA Q07869 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1946723 0.92 PTGDR2 (0.51) PTGDR2PPARDLTB4R2FFAR1PPARG
SCHEMBL1946318 0.90 PTGDR2 (0.57) PTGDR2PPARDLTB4R2FFAR1PPARG
SCHEMBL3665827 0.87 FSHR (0.38) PTGDR2LTB4R2PPARGPPARA
SCHEMBL3665828 0.87 FSHR (0.38) PTGDR2LTB4R2PPARGPPARA
SCHEMBL1948062 0.87 PTGDR2 (0.57) PTGDR2PPARDFFAR1
SCHEMBL1948807 0.86 PTGDR2 (0.59) PTGDR2PPARDLTB4R2FFAR1PPARG
SCHEMBL1951055 0.84 PTGDR2 (0.51) PTGDR2PPARDLTB4R2FFAR1
SCHEMBL1947936 0.84 PTGDR2 (0.61) PTGDR2PPARDLTB4R2PPARGPPARA
SCHEMBL1950346 0.81 PTGDR2 (0.47) PTGDR2PPARDLTB4R2FFAR1
SCHEMBL1948087 0.80 PTGDR2 (0.47) PTGDR2PPARDFFAR1PPARGPPARA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110136877-A1 2-PHENYL PHENOXYACETIC ACIDS USEFUL FOR TREATING INFLAMMATORY DISORDERS LIGAND PHARMACEUTICALS INC. (US) 2011-06-09 US claimed
US-20110136877-A1 2-PHENYL PHENOXYACETIC ACIDS USEFUL FOR TREATING INFLAMMATORY DISORDERS LIGAND PHARMACEUTICALS INC. (US) 2011-06-09 US disclosed
US-20110136877-A1 2-PHENYL PHENOXYACETIC ACIDS USEFUL FOR TREATING INFLAMMATORY DISORDERS LIGAND PHARMACEUTICALS INC. (US) 2011-06-09 US disclosed
US-20110136877-A1 2-PHENYL PHENOXYACETIC ACIDS USEFUL FOR TREATING INFLAMMATORY DISORDERS LIGAND PHARMACEUTICALS INC. (US) 2011-06-09 US disclosed
WO-2009089192-A1 2-PHENYL PHENOXYACETIC ACIDS USEFUL FOR TREATING INFLAMMATORY DISORDERS LIGAND PHARMACEUTICALS INC. (US) 2009-07-16 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110136877-A1 2-PHENYL PHENOXYACETIC ACIDS USEFUL FOR TREATING INFLAMMATORY DISORDERS HCAR2, PAH, PTGES2 PTGDR2 15/4885PPARD 404/4885LTB4R2 20/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.